Metabolites from the endophytic fungus HP-1 of Chinese eaglewood / 中国天然药物

ABSTRACT

AIM@#To study the chemical constituents from the fermentation of the endophytic fungus HP-1 of Chinese eaglewood.@*METHODS@#The chemical constituents were isolated by column chromatography on silica gel and Sephadex LH-20, and their structures were elucidated on the basis of spectroscopic analysis.@*RESULTS@#Four compounds were isolated and identified as 3α, 3β, 10β-trimethyl-decahydroazuleno[6, 7]furan-8, 9, 14-triol (1), 4-hydroxyphenylacetic acid (2), 4-hydroxyphenethyl alcohol (3), and 5-hydroxymethyl-2-furancarboxaldehyde (4).@*CONCLUSION@#Compound 1 was a new compound. Compound 2 showed antibacterial activity against Staphylococcus aureus.