Research progress on AMPK activators from natural products / 中草药

ABSTRACT

Adenosine monophosphate activated protein kinase (AMPK), known as the "energy sensor" of eukaryotic cells, is one of the targets for the treatment of metabolic diseases such as hyperlipidemia and diabetes. Natural products, with tremendous structural diversity, were an important source for drug discovery. Research progress on AMPK activators derived from natural products was reviewed according to the classification of structure, which provided a useful reference for the drug development of AMPK activators.