Progress in dipeptidyl peptidase-4 and its inhibitors / 中国药学杂志
Chinese Pharmaceutical Journal
; (24): 1789-1796, 2014.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-860145
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To review the structures of dipeptidyl peptidase-4 (DPP-4) and its inhibitors and introduce the evaluation methods of several marketed inhibitors.METHODS:
Preparation of this review is based on searching, categorizing, analyzing and summarizing of diplomatic and international literatures about DPP-4 and its inhibitors. RESULTS ANDCONCLUSION:
DPP-4 has attracted a lot of attention as a new target of type 2 diabetes, and some drug candidates have been developed and entered clinical phases. The structure-activity relationship study of various reported inhibitors could promote the development of more efficient DPP-4 inhibitors.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmaceutical Journal
Ano de publicação:
2014
Tipo de documento:
Artigo