Stability study and manufacture process optimization for Zhibai Anshen oral liquid / 药学实践杂志
Journal of Pharmaceutical Practice
; (6): 549-551, 2021.
Article
em Zh
| WPRIM
| ID: wpr-904758
Biblioteca responsável:
WPRO
ABSTRACT
Objective To optimize the manufacture process for Zhibai Anshen oral liquid. Methods The orthogonal designed experiments were conducted to monitor the effects of three factors on the content of mangiferin. The three factors included the amount of water, extraction time and alcohol precipitation concentration. Six month accelerated stability study and twelve month long term stability study were performed. Results Optimum percolation process was boiling the mixture with 10 times of water for 1 hour, followed by deposition with 60% alcohol. Conclusion This optimized process can be used for mass production.
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1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Pharmaceutical Practice
Ano de publicação:
2021
Tipo de documento:
Article