Synaptic Plasticity Regulation of Nogo-A and Development of Related Neurological Diseases (review) / 中国康复理论与实践

ABSTRACT

Axonal damage leads to permanent defects in the adult mammals central nervous system. As an important axonal growth inhibitor, Nogo-A and its receptors involve in the regulation of synaptic plasticity in mature neurons of the central nervous system, and play a role in the related neurological diseases, such as spinal cord injury, multiple sclerosis, Alzheimer's disease and posttraumatic stress disorder.