Clinical significance of co-mutation of BRAF V600E and TERT promoter in diagnosis and treatment of papillary thyroid carcinoma / 中华内分泌外科杂志
Chinese Journal of Endocrine Surgery
; (6): 551-553, 2021.
Article
em Zh
| WPRIM
| ID: wpr-907847
Biblioteca responsável:
WPRO
ABSTRACT
BRAF V600E mutation is a common gene mutation in papillary thyroid carcinoma (PTC) , which is associated with the occurrence, development, and prognosis of PTC. TERT promoter mutations are rare in PTC, but PTC with its mutations is more aggressive and has a worse prognosis. Clinically, a small number of PTC patients have both BRAF V600E mutation and TERT promoter mutations. This article provides a brief overview of the co-mutation of BRAF V600E and TERT promoter and the occurrence and development, clinical diagnosis, surgical strategies, postoperative adjuvant treatment, and prognosis of PTC.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Endocrine Surgery
Ano de publicação:
2021
Tipo de documento:
Article