A Case of Congenital Vitamin K Dependent Coaguation Factor Defeciency / 대한소아혈액종양학회지
Korean Journal of Pediatric Hematology-Oncology
; : 177-181, 1998.
Article
em Ko
| WPRIM
| ID: wpr-9695
Biblioteca responsável:
WPRO
ABSTRACT
Congenital combined deficiency of vitamin K dependent coagulation factors is a rare coagulation disorder. We experienced a 20-month old boy who was found to have a congenital vitamin K dependent coagulation factor defeciency. He presented with continuous bleeding on lacerated hard palate and had a history of numerous hemorrhagic episodes with multiple bruises after birth. Laboratory finding showed prolonged prothrombin time and partial thromboplastin time. Blood coagulation work-up showed marked decreased activities of the coagulation factors II, VII, IX, X and the natural anticoagulants proteins C and S. Assay of coagulation factors in the parents and sibling were with the normal range. There's no evidence of malabsorption, liver disease or ingestion of a coumarin compound. Response to intravenous administration of vitamin K1 was not significant but transfusion of fresh frozen plasma corrected prothrombin time and partial thromboplastin time. We reported a case of congenital combined deficiency of vitamin K dependent coagulation factors.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Pais
/
Tempo de Tromboplastina Parcial
/
Vitamina K 1
/
Plasma
/
Tempo de Protrombina
/
Valores de Referência
/
Vitamina K
/
Vitaminas
/
Coagulação Sanguínea
/
Fatores de Coagulação Sanguínea
Limite:
Humans
/
Infant
/
Male
Idioma:
Ko
Revista:
Korean Journal of Pediatric Hematology-Oncology
Ano de publicação:
1998
Tipo de documento:
Article