Endarterectomía carotídea con medición de presión de muñón, manejo hemodinámico y uso selectivo de shunt / Carotid Endarterectomy with routine carotid stump pressure measurement, intraoperative hemodynamic management and selective use of shunt

Resumen Introducción En la endarterectomía carotídea (EC) durante el clampeo, la perfusión cerebral se mantiene por circulación contralateral a través del Polígono de Willis, que se relaciona con la presión de muñón carotídeo (PM). Si ésta es menor a 50 mmHg existe riesgo de Accidente Cerebrovascular (ACV) por hipoperfusión y está indicado uso de shunt para asegurar suficiente circulación cerebral, pero también se puede elevar transitoriamente la presión arterial sistémica haciendo innecesario el uso de shunt. Objetivo Mostrar los resultados de EC con medición de PM para evaluar la perfusión cerebral del hemisferio clampeado con manejo hemodinámico intraoperatorio minimizando el uso de shunt. Material y Métodos Estudio retrospectivo de 73 pacientes sometidos a EC bajo anestesia general con medición de PM, manejo hemodinámico intraoperatorio y uso selectivo de shunt. Se analizaron variables demográficas, clínicas y morbimortalidad perioperatoria. Resultados 73 pacientes, edad promedio 71,1 años, 69,9% sintomáticos. En 54 pacientes la PM fue superior a 50 mmHg y no se usó shunt, en 19 la PM fue menor a 50 mmHg y con manejo hemodinámico intraoperatorio se elevó en 16 que no requirieron shunt. Sólo en 3 casos la PM no alcanzó los 50 mmHg y se usó un shunt de Pruitt-Inahara. Dos pacientes sintomáticos presentaron déficit neurológico central transitorio postoperatorio y 2 pacientes fallecieron por infarto cardíaco. Conclusión La EC con medición de PM y manejo hemodinámico minimizó el uso de shunt transitorio y fue un procedimiento seguro para tratar los pacientes con estenosis carotídea con indicación quirúrgica.

Introduction During carotid endarterectomy (CEA) clamping cerebral perfusion is maintained by contralateral circulation through the Circle of Willis and it is correlated to the stump pressure (SP). If it is below 50 mmHg there is risk of stroke due to hypoperfusion and a shunt must be used, but systemic blood pressure can be temporarily elevated making the use of shunt unnecessary. Aim Results of CEA with SP measurement to evaluate cerebral perfusion in cross-clamped hemisphere and hemodynamic intraoperative management reducing the use of shunt. Material and Methods Retrospective study of CEAs performed in 73 patients under general anaesthesia with SP measurement, hemodynamic management and selective use of shunt. Demographics, clinical and perioperative morbimortality variables were analized. Results 73 patients, average age 71.1 years, 69.9% symptomatic. In 54 patients SP was above 50 mmHg and shunt was not used, in 19 SP was below 50 mmHg, it was elevated through intraoperative hemodynamic management and shunt was not needed. In only 3 cases SP did not reach 50 mmHg and a Pruitt-Inahara shunt was used. Two patients presented postoperative transient central neurological deficit and 2 died due to myocardial infarction. Conclusion CEA with SP measurement and hemodynamic management reduced the use of carotid shunting and it was a safe procedure to treat patients with severe carotid stenosis who need surgical intervention.

Morphological and hemodynamic patterns of carotid stenosis treated by endarterectomy with patch closure versus stenting: a duplex ultrasound study

OBJECTIVES: A duplex ultrasound study was performed to investigate morphological and hemodynamic patterns of carotid stenoses treated by endarterectomy with patch closure versus stenting. MATERIALS AND METHOD: Twenty-nine carotid stenoses were treated with stenting and 65 with patch closure. Duplex ultrasound parameters (luminal diameter, mm; peak systolic velocity and end-diastolic velocity, cm/s) were measured 24 hours after the procedures and also at 12 months post-procedure. Residual stenoses (immediately postprocedure) and restenoses (within 12 months of procedure) were defined as narrowings of >50 percent on duplex ultrasound examination. RESULTS: In stented patients, the luminal diameter of the proximal internal carotid artery increased in the interval between the 24-hour and 12-month post-procedure studies, while in the patch closure patients, the diameter decreased. Carotid hemodynamics normalized immediately after both patching and stenting and remained relatively stable thereafter up to 12 months. No statistically elevated flow velocities (in the absence of residual stenosis or restenosis) were observed in the patched or stented carotid arteries. No significant differences in residual stenosis rates were observed between the stenting group (3 cases, 10.34 percent) and the patch closure group (1 case, 1.53 percent, P = 0.08). At 12 months, 2 stenting patients (6.88 percent) and 2 patch closure patients (3.07 percent) had $50 percent restenosis (P = 0.58). One case of late stroke due to restenosis was observed in the stenting group; the patient died 12 months postoperatively, before receiving new intervention. CONCLUSION: Measurements over time in luminal diameter signalized differences in arterial remodeling mechanisms between patched and stented carotids. Both stenting and patch closure were associated with carotid patency and flow restoration. This study does not support a general approach to new velocity criteria indiscriminately applied to stented or patched carotids.

Estudio con ultrasonido doppler color en la caracterización de la enfermedad aterosclerotica carotidea oclusiva sintomática / Study with color doppler ultrasound in the characterization of symptomatic carotid atherosclerotic occlusive disease

Objective: To determine the association between risk factors and atherosclerosis in the carotid arteries in occlusive cerebrovascular disease. Method: A prospective, descriptive, cross-sectional study in 274 patients with clinical and CT diagnosis ofischemic ictus was conducted. Examination by the means of carotid artery color Doppler ultrasound was performed in the study Group. Results and Conclusions: The mean age of patients was 68.7 years anda male predominance (54.1 percent) was reported. Arterial hypertension, which was present in 214 patients (78.1 percent), constituted the most prevalent atherogenic risk factor, followed by age over 60 years (75.9 percent), and smoking (58 percent). The atherothrombotic and cardioembolic origins were predominant (54 percent and 19.7 percent, respectively), followed by lacunar (13.9 percent), and undetermined origin (11.3 percent). Atherosclerotic involvement occurs bilaterally with a predominance of the right axis, appearing low shear stress areas as the sites of the greatest severity.

Objetivo: Determinar la asociación entre los factores de riesgos y la aterosclerosis de las arterias carótidas, en la enfermedad cerebrovascular oclusiva. Método: Se realizó un estudio prospectivo, descriptivo y transversal en 274 pacientes con diagnóstico clínico y tomográfico de ictus isquémico, realizándoles estudio con ultrasonido Doppler color carotídeo. Resultados y Conclusiones: La edad media de los pacientes fue 68,7años. Se observó predominio de sexo masculino (54,1 por ciento). EI factor de riesgo aterogénico que predominó fue HTA, presente en 214 (78.1 por ciento), seguido por edad mayor de 60 (75.9 por ciento) y tabaquismo (58 por ciento). El origen aterotrombótico y cardioembólico fueron predominantes (54 y 19.7 por ciento respectivamente), seguidos por el lacunar (13.9 por ciento) y el origen indeterminado (11.3 por ciento). La afectación aterosclerótica ocurre bilateralmente, con un predominio del eje derecho, siendo las zonas de bajo shear stress los sectores de mayor severidad.