Chronic granulomatous disease of childhood: differential diagnosis and prognosis
Rev. paul. med
; 111(6): 472-6, nov.-dez. 1993. tab, graf
Article
em En
| LILACS
| ID: lil-130200
Biblioteca responsável:
BR1.1
RESUMO
Of a total of 111 children with primary immunodeficiency, 20 had phagocytic disorders (18 per cent) and 10 of them (8 boys and 2 girls) were diagnosed as chronic granulomatous disease (CGD). The children presented with repeated infections already during the first months of life. The main clinical findings were: abscess (n=8), otitis (n=8), pneumonia (n=8), lymphadenitis and pyodermits (n=6) and septicemia (4), NBT reduction was almost absent in all the children, except one of them. Bactericidal activity against S. aureus and phagocytosis were impaired in CGD patients. Different patterns of laboratory tests and prognosis were observed and girls had a better evolution
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Temas:
Informacoes_doencas_cronicas_degenerativas
Base de dados:
LILACS
Assunto principal:
Doença Granulomatosa Crônica
Idioma:
En
Revista:
Rev. paul. med
Assunto da revista:
MEDICINA
Ano de publicação:
1993
Tipo de documento:
Article