Detalhe da pesquisa
1.
Cutaneous manifestations in Costello syndrome: HRAS p.Gly12Ser affects RIN1-mediated integrin trafficking in immortalized epidermal keratinocytes.
Hum Mol Genet
; 32(2): 304-318, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35981076
2.
A comprehensive analysis of RAS-effector interactions reveals interaction hotspots and new binding partners.
J Biol Chem
; 296: 100626, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33930461
3.
Activating MRAS mutations cause Noonan syndrome associated with hypertrophic cardiomyopathy.
Hum Mol Genet
; 29(11): 1772-1783, 2020 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31108500
4.
Activating Mutations of RRAS2 Are a Rare Cause of Noonan Syndrome.
Am J Hum Genet
; 104(6): 1223-1232, 2019 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31130282
5.
The intramolecular allostery of GRB2 governing its interaction with SOS1 is modulated by phosphotyrosine ligands.
Biochem J
; 478(14): 2793-2809, 2021 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34232285
6.
CDC42-IQGAP Interactions Scrutinized: New Insights into the Binding Properties of the GAP-Related Domain.
Int J Mol Sci
; 23(16)2022 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36012107
7.
Selectivity Determinants of RHO GTPase Binding to IQGAPs.
Int J Mol Sci
; 22(22)2021 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34830479
8.
Correction: Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.
PLoS Genet
; 13(6): e1006843, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28622382
9.
Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.
PLoS Genet
; 13(3): e1006684, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28346493
10.
Aberrant HRAS transcript processing underlies a distinctive phenotype within the RASopathy clinical spectrum.
Hum Mutat
; 38(7): 798-804, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28390077
11.
The Role of Embryonic Stem Cell-expressed RAS (ERAS) in the Maintenance of Quiescent Hepatic Stellate Cells.
J Biol Chem
; 291(16): 8399-413, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26884329
12.
IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES.
J Biol Chem
; 291(51): 26364-26376, 2016 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27815503
13.
Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
J Biol Chem
; 291(39): 20353-71, 2016 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27481945
14.
Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis.
Hum Mol Genet
; 23(16): 4315-27, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24705357
15.
The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.
J Biol Chem
; 289(1): 74-88, 2014 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24273164
16.
Functional cross-talk between ras and rho pathways: a Ras-specific GTPase-activating protein (p120RasGAP) competitively inhibits the RhoGAP activity of deleted in liver cancer (DLC) tumor suppressor by masking the catalytic arginine finger.
J Biol Chem
; 289(10): 6839-6849, 2014 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24443565
17.
Functional Classification and Interaction Selectivity Landscape of the Human SH3 Domain Superfamily.
Cells
; 13(2)2024 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38275820
18.
SIRT4 as a novel interactor and candidate suppressor of C-RAF kinase in MAPK signaling.
Life Sci Alliance
; 7(6)2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38499327
19.
SH3-mediated targeting of Wrch1/RhoU by multiple adaptor proteins.
Biol Chem
; 394(3): 421-32, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23183748
20.
Rho-kinase: regulation, (dys)function, and inhibition.
Biol Chem
; 394(11): 1399-410, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23950574