Detalhe da pesquisa
1.
Genetic ablation of cyclooxygenase-2 in keratinocytes produces a cell-autonomous defect in tumor formation.
Carcinogenesis
; 33(11): 2293-300, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22902545
2.
Discovery of LY2457546: a multi-targeted anti-angiogenic kinase inhibitor with a novel spectrum of activity and exquisite potency in the acute myelogenous leukemia-Flt-3-internal tandem duplication mutant human tumor xenograft model.
Invest New Drugs
; 30(3): 936-49, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21360050
3.
Cyclooxygenase-2 inhibits UVB-induced apoptosis in mouse skin by activating the prostaglandin E2 receptors, EP2 and EP4.
Cancer Res
; 67(5): 2015-21, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17332329
4.
Genetic deficiency or pharmacological inhibition of cyclooxygenase-1 or -2 induces mouse keratinocyte differentiation in vitro and in vivo.
FASEB J
; 18(1): 185-7, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14630706
5.
Dose study of the multikinase inhibitor, LY2457546, in patients with relapsed acute myeloid leukemia to assess safety, pharmacokinetics, and pharmacodynamics.
Cancer Manag Res
; 3: 157-75, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21625399
6.
Cyclooxygenase-2 deficiency increases epidermal apoptosis and impairs recovery following acute UVB exposure.
Mol Carcinog
; 46(5): 354-62, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17238138
7.
The effects of aspirin on gastric mucosal integrity, surface hydrophobicity, and prostaglandin metabolism in cyclooxygenase knockout mice.
Gastroenterology
; 127(1): 94-104, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15236176