Detalhe da pesquisa
1.
γ-Secretase Modulator BPN15606 Reduced Aß42 and Aß40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome.
Ann Neurol
; 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38747498
2.
Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model.
Alzheimers Dement
; 18(6): 1203-1234, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34757693
3.
Apolipoprotein E/Amyloid-ß Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4.
Am J Pathol
; 189(8): 1621-1636, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31108099
4.
Synaptic Amyloid-ß Oligomers Precede p-Tau and Differentiate High Pathology Control Cases.
Am J Pathol
; 186(1): 185-98, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26718979
5.
Monoclonal antibodies against Aß42 fibrils distinguish multiple aggregation state polymorphisms in vitro and in Alzheimer disease brain.
J Biol Chem
; 289(46): 32131-32143, 2014 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25281743
6.
Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques.
Neurobiol Dis
; 71: 53-61, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25092575
7.
Relationships among body mass, brain size, gut length, and blood tryptophan and serotonin in young wild-type mice.
BMC Physiol
; 9: 4, 2009 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19321004
8.
Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease.
Mol Neurodegener
; 13(1): 11, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29490706
9.
Effective anti-Alzheimer Aß therapy involves depletion of specific Aß oligomer subtypes.
Neurol Neuroimmunol Neuroinflamm
; 3(3): e237, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27218118
10.
Positron emission tomography imaging of fibrillar parenchymal and vascular amyloid-ß in TgCRND8 mice.
ACS Chem Neurosci
; 4(4): 613-23, 2013 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23509918
11.
Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice.
Mol Neurodegener
; 7: 37, 2012 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22866920
12.
Transient expression of serotonin 5-HT4 receptors in the mouse developing thalamocortical projections.
Dev Neurobiol
; 70(3): 165-81, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19998416
13.
Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aß oligomers.
Mol Neurodegener
; 5: 57, 2010 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21144050