Detalhe da pesquisa
1.
Targeting the m6A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication.
Genes Dev
; 35(13-14): 1005-1019, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34168039
2.
Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases.
Bioorg Med Chem Lett
; 23(15): 4381-7, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23773865
3.
The PARP1 Inhibitor AZD5305 Impairs Ovarian Adenocarcinoma Progression and Visceral Metastases in Patient-derived Xenografts Alone and in Combination with Carboplatin.
Cancer Res Commun
; 3(3): 489-500, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36994441
4.
Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity.
Cancer Discov
; 13(10): 2228-2247, 2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37548590
5.
Design and Preclinical Evaluation of a Novel B7-H4-Directed Antibody-Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305.
Clin Cancer Res
; 29(6): 1086-1101, 2023 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36355054
6.
Hypoxia-selective targeting by the bioreductive prodrug AQ4N in patients with solid tumors: results of a phase I study.
Clin Cancer Res
; 14(4): 1096-104, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18281542
7.
Selective tumor targeting by the hypoxia-activated prodrug AQ4N blocks tumor growth and metastasis in preclinical models of pancreatic cancer.
Clin Cancer Res
; 13(7): 2216-25, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17404106
8.
A role for polymerase eta in the cellular tolerance to cisplatin-induced damage.
Cancer Res
; 65(21): 9799-806, 2005 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16267001
9.
The overexpression of specialized DNA polymerases in cancer.
DNA Repair (Amst)
; 4(5): 583-93, 2005 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15811630
10.
The RON receptor tyrosine kinase promotes metastasis by triggering MBD4-dependent DNA methylation reprogramming.
Cell Rep
; 6(1): 141-54, 2014 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24388747
11.
In vivo activation of the hypoxia-targeted cytotoxin AQ4N in human tumor xenografts.
Mol Cancer Ther
; 8(12): 3266-75, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19996276