RESUMO
Hypertension (HT) is one of the main risk factors for cardiovascular disease (CVD). Although it is a global problem, independently of economic situation, region, race or culture, the data available on Latin America are limited. Clinical guidelines emphasise the importance of obtaining reliable blood pressure readings. For this reason, the use of ambulatory blood pressure monitoring (ABPM) is recommended. This improves precision and reproducibility, resulting in better diagnosing and therapeutic decision-making, and constitutes a better estimation of prognosis than office measurements. Unfortunately, there is no global prospective ABPM registry for all of Latin America that analyses HT prevalence, the level of knowledge about it, treatment percentage and the degree of control. Consequently, the authors of this article consider its implementation a priority.
Assuntos
Monitorização Ambulatorial da Pressão Arterial , Hipertensão , Pressão Sanguínea , Humanos , Hipertensão/epidemiologia , Estudos Prospectivos , Sistema de Registros , Reprodutibilidade dos Testes , Estados UnidosRESUMO
AIM: To evaluate the effectiveness of botulinum toxin in the treatment of upper and lower limb spasticity in pediatric patients in a real clinical setting. PATIENTS AND METHODS: A retrospective study was conducted based on information from clinical records of 79 pediatric patients with spasticity in different clinical forms and severity treated with botulinum toxin type A. The improvement of rigidity and mobility was estimated by the attending physician through physical examination, evaluating the gait, rating on the Ashworth scale and measurement of joint mobility angles using a goniometer. The number of injections, the interval between them, the site of application and the dose were recorded, considering the reduction of at least one point on the Ashworth scale or an increase in the degrees of joint mobility as treatment response. RESULTS: Patients received injections in a mean of 10 ± 7 muscles at intervals of 4 to 50 weeks (average: 13 ± 9 weeks). A 90% also received rehabilitation. The knee, ankle and wrist showed presented a higher percentage of improvement. An improvement in the degrees of movement was found in 24% of patients. CONCLUSION: The application of botulinum toxin type A was effective for the treatment of spasticity in the pediatric population.
TITLE: Dosis y eficacia de la toxina botulinica en pacientes pediatricos con espasticidad.Objetivo. Evaluar la efectividad de la toxina botulinica en el tratamiento de la espasticidad de los miembros superiores e inferiores en pacientes pediatricos en un entorno clinico real. Pacientes y metodos. Se realizo un estudio retrospectivo basado en el historial clinico de 79 pacientes pediatricos con espasticidad en diferentes formas clinicas y grados de afectacion tratados con toxina botulinica tipo A. La mejoria de la rigidez y movilidad fue estimada por el medico tratante mediante exploracion fisica, evaluando la marcha, la calificacion en la escala de Ashworth y la medicion de los angulos de movilidad articular mediante un goniometro. Se registro el numero de inyecciones, el intervalo entre ellas, el sitio de aplicacion y la dosis, y se considero una respuesta positiva al tratamiento la disminucion del al menos un punto en la escala de Ashworth o un incremento en los grados de movilidad articular. Resultados. Los pacientes recibieron inyecciones en 10 ± 7 musculos diferentes en intervalos de 4 a 50 semanas (media: 13 ± 9 semanas). Un 90% de los pacientes recibio rehabilitacion. Las articulaciones de la rodilla, el tobillo y la muñeca presentaron un mayor porcentaje de mejoria. En el 24% de los pacientes se encontro mejoria en los grados de movimiento articular. Conclusion. La aplicacion de toxina botulinica tipo A fue efectiva para el tratamiento de la espasticidad en la poblacion pediatrica.
Assuntos
Toxinas Botulínicas Tipo A/administração & dosagem , Espasticidade Muscular/tratamento farmacológico , Fármacos Neuromusculares/administração & dosagem , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Estudos Retrospectivos , Resultado do TratamentoRESUMO
La hipertensión arterial (HTA) es el principal factor de riesgo de enfermedad cardiovascular. Aunque es un problema global, independiente de la situación económica, región, raza o cultura, los datos disponibles con respecto a Latinoamérica no son muy abundantes. Por otra parte, las guías clínicas enfatizan la importancia de obtener lecturas fiables de la presión arterial. Por ello, se recomienda el uso de la monitorización ambulatoria de la presión arterial (MAPA), que mejora su precisión y reproducibilidad, ayudando a un mejor diagnóstico, en la toma de decisiones terapéuticas, y representa una mejor estimación pronóstica que las medidas en consulta. Lamentablemente, no existe ningún registro prospectivo global de MAPA para toda Latinoamérica que analice la prevalencia de HTA, el grado de su conocimiento, su porcentaje de tratamiento y el grado de control. En consecuencia, los autores de este artículo consideran prioritaria su puesta en marcha (AU)
Hypertension (HT) is one of the main risk factors for cardiovascular disease. Although it is a global problem, independently of economic situation, region, race or culture, the data available on Latin America are limited. Clinical guidelines emphasise the importance of obtaining reliable blood pressure readings. For this reason, the use of ambulatory blood pressure monitoring (ABPM) is recommended. This improves precision and reproducibility, resulting in better diagnosing and therapeutic decision-making, and constitutes a better estimation of prognosis than office measurements. Unfortunately, there is no global prospective ABPM registry for all of Latin America that analyses HT prevalence, the level of knowledge about it, treatment percentage and the degree of control. Consequently, the authors of this article consider its implementation a priority (AU)
Assuntos
Humanos , Monitorização Ambulatorial da Pressão Arterial , Hipertensão/epidemiologia , Hipertensão/prevenção & controle , América Latina/epidemiologiaRESUMO
A multicenter, open, prospective study was carried out to establish the efficacy and safety of quinapril 10.0, 20.0, or 40.0 mg, or 20 mg plus 12.5 mg hydrochlorothiazide (HCTZ) given once daily in 256 patients with mild-to-moderate essential hypertension treated in primary care units in Mexico. The study consisted of a 4-week placebo washout period, followed by 12 weeks of active treatment. Quinapril doses were titrated upward at 4-week intervals to three dosage levels. Patients who did not respond to 20-mg doses were randomly assigned to receive 40 mg quinapril daily or 20 mg quinapril plus 12.5 mg HCTZ daily until the end of the study. Quinapril was useful as monotherapy in 78% of the 256 patients (92.9% of patients who completed the study were evaluable): 73.3% of patients required only 10 mg, and their average blood pressure was similar to that of patients who required doses of greater than 10 mg. Only 12.2% of responsive patients required either 40 mg of quinapril or 20 mg of quinapril plus HCTZ 12.5 mg. Quinapril was equally effective and safe in elderly patients (> 60 years old) and in obese and nonobese patients. A low incidence of adverse effects in our patients confirms quinapril's safety, and no adverse changes were observed in laboratory tests.
Assuntos
Hipertensão/tratamento farmacológico , Isoquinolinas/uso terapêutico , Tetra-Hidroisoquinolinas , Adolescente , Adulto , Fatores Etários , Idoso , Pressão Sanguínea/efeitos dos fármacos , Feminino , Hospitais Gerais , Humanos , Isoquinolinas/farmacologia , Masculino , México , Pessoa de Meia-Idade , Atenção Primária à Saúde , Estudos Prospectivos , QuinaprilRESUMO
A drug surveillance study was performed to determine the tolerance and safety of quinapril in the treatment of patients with stage 1 or 2 hypertension. The trial was noncomparative, open-label, uncontrolled, and nonrandomized. Patients with secondary hypertension, heart failure, other heart diseases, and other serious conditions were excluded. After a washout period of 2 weeks, 752 patients (316 men and 436 women) with diastolic blood pressure (DBP) between 90 and 115 mm Hg and systolic blood pressure (SBP) between 140 and 200 mm Hg were entered into the treatment phase. The mean age of patients (+/- SD) was 53.1 +/- 11.4 years. Patients initially received 10 mg/d quinapril for 4 weeks. For nonresponders, the dosage was titrated up to a maximum of 40 mg. Active treatment continued for 12 weeks. Initial blood pressures (mean +/- SD) were DBP, 102 +/- 6.1 mm Hg, and SBP, 163 +/- 14.4 mm Hg. Final blood pressures were DBP, 83 +/- 6.5 mm Hg, and SBP, 135 +/- 11.6 mm Hg. The response rate for the therapeutic goal (DBP < 90 mm Hg and SBP < 140 mm Hg, or a reduction in SBP > or = 20 mm Hg) was 67.1%; 41 patients did not complete the study. The most common adverse events were cough, headache, and dizziness; only 10 patients (1.3%) failed to complete the study because of adverse events. Quinapril, as used in current private clinical practice, is well tolerated and effective for the treatment of patients with stage 1 or 2 hypertension.
Assuntos
Anti-Hipertensivos/uso terapêutico , Hipertensão/tratamento farmacológico , Isoquinolinas/uso terapêutico , Tetra-Hidroisoquinolinas , Adulto , Idoso , Idoso de 80 Anos ou mais , Anti-Hipertensivos/administração & dosagem , Anti-Hipertensivos/efeitos adversos , Pressão Sanguínea/efeitos dos fármacos , Relação Dose-Resposta a Droga , Feminino , Humanos , Isoquinolinas/administração & dosagem , Isoquinolinas/efeitos adversos , Masculino , Pessoa de Meia-Idade , QuinaprilRESUMO
A meta-analysis was performed to examine the therapeutic effect of quinapril in the treatment of patients with mild-to-moderate hypertension. Data from three clinical trials conducted in Mexico and including a total of 426 patients were examined using a retrospective approach and statistical methods. The meta-analysis proved that quinapril induces positive diastolic and systolic responses at all the doses studied, particularly at the 10-mg dose. At this dose, 94.1% of patients reduced their diastolic blood pressure (DBP) by 10 mm Hg or attained a DBP of < or = 90 mm Hg. Overall, quinapril reduced DBP by between 14.8 and 24.8 mm Hg proportionally to the baseline DBP. Systolic blood pressure decreased 16 to 35.7 mm Hg from baseline levels. We conclude that the meta-analysis allowed a clearer and more dependable handling of the results regarding effectiveness and optimum dose of quinapril.
Assuntos
Anti-Hipertensivos/uso terapêutico , Hipertensão/tratamento farmacológico , Isoquinolinas/uso terapêutico , Tetra-Hidroisoquinolinas , Adulto , Idoso , Anti-Hipertensivos/administração & dosagem , Pressão Sanguínea/efeitos dos fármacos , Feminino , Humanos , Hidroclorotiazida/uso terapêutico , Hipertensão/fisiopatologia , Isoquinolinas/administração & dosagem , Masculino , México , Pessoa de Meia-Idade , QuinaprilRESUMO
Some active interventions to modify risk factors paradoxically introduce new risk per se, but benefits in extensive populations vastly offset the proportionally small hazards introduced by these maneuvers. However, in daily practice, this potential source of danger can be crucial in a given patient in whom the new potential risk can be greater than the disease that one is trying to prevent or treat. Patients in whom risk factor modification introduces a new risk should be identified before it is decided who, when, and how to treat. The clinical profiles of these patients, with special reference to the negative effects of risk factor intervention on the heart, are discussed in this article.
Assuntos
Cardiopatias/etiologia , Hipertensão/terapia , Antagonistas Adrenérgicos beta/efeitos adversos , Anti-Hipertensivos/efeitos adversos , Depressores do Apetite/efeitos adversos , Arritmias Cardíacas/etiologia , Cardiomegalia/induzido quimicamente , Cardiomegalia/etiologia , Doença das Coronárias/etiologia , Doença das Coronárias/mortalidade , Coração/fisiopatologia , Cardiopatias/induzido quimicamente , Humanos , Hipertensão/etiologia , Hipoglicemiantes/efeitos adversos , Hipolipemiantes/efeitos adversos , Esforço Físico , RiscoRESUMO
OBJECTIVE: The main objective of this study was to evaluate well-being and physical activity of 248 hypertensive patients, including 177 females, who had previously been included in the Latin-American Study on Lacidipine in Hypertension (LASTLHY). SUBJECTS, MATERIALS AND METHODS: This open study was carried out in 12 clinical centers in Argentina, Brazil, Colombia, Mexico and Venezuela, to compare, over a period of 16 weeks, the antihypertensive action of a fixed-dose, once daily of 4 mg lacidipine administered orally to 120 patients and 30 mg nifedipine GITS (Gastro-Intestinal Therapeutic System) administered to 128 patients, aged between 40 and 65 years. All patients had mild to moderate hypertension and treatment was begun at the end of a one-week placebo run-in period (end of week -1). Well-being and physical activity were assessed by means of single questionnaire, which reflected the physical and cultural diversities amongst the clinical centers and patients. The questionnaire included 13 multiple-choice and 8 contingent open questions. The score of each question was multiplied by a coefficient related to the importance of each question to the patient (semipersonalization); the coefficient was obtained from cultural and socioeconomic data collected at the time of enrollment. The semipersonalization was carried out by a blind psychological study with respect to the medication and had a high repeatability in the assignment of personalized coefficients to the score of each question. The scores of each question were added to obtain an overall well-being and activity scoring. The possible theoretical range for the overall scoring in this study was 10 - 124. RESULTS: See Table 1. CONCLUSION: The study revealed that the administration of calcium channel blockers such as lacidipine and nifedipine GITS, and lacidipine in particular, produced low incidence of side effects, and lacidipine in particular induced significant improvement in the quality of life.
Assuntos
Anti-Hipertensivos/uso terapêutico , Bloqueadores dos Canais de Cálcio/uso terapêutico , Di-Hidropiridinas/uso terapêutico , Hipertensão/tratamento farmacológico , Hipertensão/psicologia , Nifedipino/uso terapêutico , Qualidade de Vida , Atividades Cotidianas , Administração Oral , Adulto , Idoso , Exercício Físico , Feminino , Inquéritos Epidemiológicos , Humanos , Masculino , Pessoa de Meia-Idade , PsicometriaRESUMO
In order to study the efficacy and tolerance of isradipine, a new Ca++ antagonist for the treatment of stable chronic angina, a multicentric cooperative study was carried out in eight Latin American countries (Argentine, Chile, Colombia, Ecuador, Mexico, Peru, Uruguay and Venezuela), which included 169 patients (60% men and 40% women), average age 62.6 +/- 9.7. Patients with more than 4 biweekly anginal crisis were accepted, with one or more of the following inclusion criteria: coronariographic evidence of obstruction greater than 60% in one or more vessels, IAM history, positive scintigraphy and positive effort test. The trial was single-blind, with placebo during the admission phase (2 weeks) and active treatment for 12 weeks. isradipine was administered in increasing doses of 2.5, 5, and 7 mg thrice a day, according to the presence or absence of anginal crisis. It was observed that the average frequency of weekly pains decreased from 8.2 +/- 7 under placebo to 6.3 +/- 7.5 under isradipine at low doses, and to 2.0 +/- 2.0 (p less than 0.001) under maximum doses. TNT intake decreased parallel also in a significant way. At the end of the trial, 37% of patients had become asymptomatic, and angina had reduced to less than two crisis a week in 33%. A clear relation doses-effect was observed. There was no alteration in laboratory exams neither in ECG. Seven patients had complications derived from the evolutional course of disease (2 IAM, 5 unstable angina and one sudden death). Adverse events were relatively frequent and the majority derived from vasodilator effect (tibial oedema 37%, flushing 17%, headache 23%).(ABSTRACT TRUNCATED AT 250 WORDS)
Assuntos
Angina Pectoris/tratamento farmacológico , Bloqueadores dos Canais de Cálcio/uso terapêutico , Piridinas/uso terapêutico , Adulto , Idoso , Idoso de 80 Anos ou mais , Angina Pectoris/epidemiologia , Angina Pectoris/fisiopatologia , Bloqueadores dos Canais de Cálcio/efeitos adversos , Doença Crônica , Relação Dose-Resposta a Droga , Feminino , Hemodinâmica/efeitos dos fármacos , Humanos , Isradipino , América Latina , Masculino , Pessoa de Meia-Idade , Piridinas/efeitos adversos , Método Simples-CegoRESUMO
An 8-week, randomized, double-blind study comparing the efficacy and tolerability of policosanol and acipimox was conducted in patients with type II hypercholesterolemia. Prior to entry into active treatment, all patients followed a standard cholesterol-lowering diet for 12 weeks. Sixty-three patients were randomized to receive either policosanol (10 mg/day) or acipimox (750 mg/day) tablets for 8 weeks under double-blind conditions. Both groups were similar at randomization. Policosanol significantly reduced total cholesterol (p < 0.0001) (15.8%), low-density lipoprotein (LDL)-cholesterol (21%) and the ratios of LDL-cholesterol to high-density lipoprotein (HDL)-cholesterol (15.8%) and cholesterol to HDL-cholesterol (11.5%). Acipimox significantly lowered both cholesterol and LDL cholesterol by 7.5%. The percent changes of total cholesterol, LDL-cholesterol and both ratios were larger in the policosanol group than in the acipimox group. Both drugs were well tolerated. Acipimox significantly increased (p > 0.001) aspartate amino transferase levels but only four patients showed increases above the normal limit. Policosanol significantly reduced creatinine values (p > 0.05) but no patients had values out of the normal range. Four patients withdrew from the study (two from each group) but none withdrew because of adverse effects. No adverse effects were reported in the policosanol group, while five patients on acipimox reported adverse effects (hot flushes, nausea, vomiting, headache, hypochondrial pain and leg edema). These results indicate that policosanol (10 mg/day) was more effective and well tolerated than was acipimox (750 mg/day) in this study population.
Assuntos
Anticolesterolemiantes/administração & dosagem , Álcoois Graxos/administração & dosagem , Hiperlipoproteinemia Tipo II/tratamento farmacológico , Hipolipemiantes/administração & dosagem , Pirazinas/administração & dosagem , Idoso , Anticolesterolemiantes/efeitos adversos , Método Duplo-Cego , Álcoois Graxos/efeitos adversos , Feminino , Humanos , Hipolipemiantes/efeitos adversos , Masculino , Pessoa de Meia-Idade , Pirazinas/efeitos adversos , Resultado do TratamentoRESUMO
The efficacy and safety of once-daily telmisartan 80 mg vs. once-daily enalapril 20 mg in the treatment of essential hypertension were evaluated in a multicentre, single-blind, placebo-controlled, randomised trial. In total, 68 patients (49 females, 19 males) with mild-to-moderate hypertension, defined as morning supine systolic blood pressure (SBP) 141-149 mmHg, diastolic blood pressure (DBP) 95-114 mmHg, were enrolled. After a 4-week placebo run-in phase, patients were randomly assigned to treatment with telmisartan or enalapril administered once daily in the morning for 8 weeks. No statistically significant differences were found in the baseline characteristics of patients in either group. Both SBP and DBP were decreased in both treatment groups, but the reductions were statistically different in favour of telmisartan (SBP, p = 0.013; DBP, p = 0.002). The incidence of adverse effects was lower in the telmisartan group, with the absence of cough. In conclusion, telmisartan is more effective and better tolerated than enalapril for the treatment of hypertension and has the advantage that it does not cause cough.
Assuntos
Bloqueadores do Receptor Tipo 1 de Angiotensina II/administração & dosagem , Inibidores da Enzima Conversora de Angiotensina/administração & dosagem , Anti-Hipertensivos/administração & dosagem , Benzimidazóis/administração & dosagem , Benzoatos/administração & dosagem , Hipertensão/tratamento farmacológico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Bloqueadores do Receptor Tipo 1 de Angiotensina II/efeitos adversos , Inibidores da Enzima Conversora de Angiotensina/efeitos adversos , Anti-Hipertensivos/efeitos adversos , Benzimidazóis/efeitos adversos , Benzoatos/efeitos adversos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Método Simples-Cego , TelmisartanRESUMO
The objective of this open-label, parallel-group comparative study was to assess the clinical efficacy and safety of once-daily treatment for 8 weeks with telmisartan 80 mg in comparison with atenolol 50 mg on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in patients with mild-to-moderate hypertension (morning supine SBP 141-199 mmHg, DBP 95-114 mmHg). A total of 58 patients were enrolled. The comparability of the two treatment groups was statistically documented at the beginning of the study. Telmisartan was more effective than atenolol, with a decrease in SBP of 21.7 mmHg vs. 11.8 mmHg (p = 0.03) and a non-significant decrease in DBP of 14.7 mmHg vs. 10.1 mmHg. The safety profiles of both drugs were very similar; both drugs were well tolerated. In conclusion, once-daily telmisartan 80 mg is more effective than once-daily atenolol 50 mg in lowering SBP with no negative chronotropism. Furthermore, telmisartan was as well tolerated as atenolol in the treatment of mild-to-moderate essential hypertension in adults.
Assuntos
Bloqueadores do Receptor Tipo 1 de Angiotensina II/administração & dosagem , Inibidores da Enzima Conversora de Angiotensina/administração & dosagem , Anti-Hipertensivos/administração & dosagem , Atenolol/administração & dosagem , Benzimidazóis/administração & dosagem , Benzoatos/administração & dosagem , Hipertensão/tratamento farmacológico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Bloqueadores do Receptor Tipo 1 de Angiotensina II/efeitos adversos , Inibidores da Enzima Conversora de Angiotensina/efeitos adversos , Anti-Hipertensivos/efeitos adversos , Atenolol/efeitos adversos , Benzimidazóis/efeitos adversos , Benzoatos/efeitos adversos , Pressão Sanguínea/fisiologia , Método Duplo-Cego , Feminino , Humanos , Hipertensão/fisiopatologia , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Telmisartan , Resultado do TratamentoAssuntos
Anti-Hipertensivos/uso terapêutico , Hipertensão/tratamento farmacológico , Adulto , Idoso , Doenças Cardiovasculares/complicações , Doenças Cardiovasculares/prevenção & controle , Conferências de Consenso como Assunto , Análise Custo-Benefício , Gerenciamento Clínico , Medicina Baseada em Evidências , Feminino , Comportamentos Relacionados com a Saúde , Saúde Holística , Humanos , Hipertensão/complicações , Hipertensão/terapia , Estilo de Vida , Masculino , Pessoa de Meia-Idade , Risco , Determinantes Sociais da SaúdeRESUMO
Introducción: La asistencia al niño hospitalizado y su familia es uno de los ámbitos que hoy requiere un esfuerzo por investigar. Conocer los factores relacionados con la ansiedad que viven los familiares en la UCIP, abre caminos para desarrollar modelos de intervención y Planes de Cuidados de Enfermería dirigidos a favorecer el afrontamiento y mejorar el bienestar familiar intrahospitalario. Objetivo: Determinar la relación de los factores sociodemográficos y hospitalarios con el nivel de ansiedad que presentan los familiares con pacientes hospitalizados en la unidad de cuidados intensivos pediátricos (UCIP). Metodología: Estudio cuantitativo, descriptivo y transversal. Se utilizó un instrumento de elaboración propia para la identificación de factores sociodemográficos y hospitalarios; y la escala de Inventario de Ansiedad Estado-Rasgo de Spielberger (IDARE) para la medición del nivel de ansiedad. Resultados: 34 familiares que participaron -11.8% (4) hombres; y 88.2% (30) mujeres- la edad promedio fue de 29 años, las puntuaciones de ansiedad estado y ansiedad rasgo indican que al no conocer algún albergue se presenta una diferencia significativa en el nivel de ansiedad estado de los familiares (X
Introduction: Aid to hospitalized children and their relatives is an issue which requires further research. Knowing the factors related to the anxiety that these children's relatives experience in the PIUC can broaden the scope to develop intervention models and Nursing Care Plans to address these issues and improve the intra-hospital family wellbeing. Objective: To determine the relationship between the social, demographic, and hospital factors with the levels of anxiety experienced by the relatives of hospitalized patients in the Pediatric Intensive Care Unit (PICU). Methodology: Quantitative, descriptive, and transversal study. An own-designed instrument to identify social, demographic, and hospital factors, and the Spielberger's State-Trait Anxiety Inventory (STAI) to estimate the levels of anxiety were used. Results: Thirty four relatives participated, 11.8% (4) were male and 88.2% (30) female. The average age was 29 years old. The anxiety state and trait scores suggest that, when information on shelters in not available, there are significant differences in the state of anxiety (X
Introduçãoa: assistência da criança hospitalizada e da sua família, é um dos âmbitos que na atualidade requer um esforço para pesquisar. Conhecer os fatores relacionados com a ansiedade que experimentam os familiares na UCIP, abre caminhos para desenvolver modelos de intervenção e Planos de Cuidados de Enfermagem dirigidos a favorecer o enfrentamento e melhorar o bem-estar familiar intra-hospitalar. Objetivo: Determinar a relação dos fatores sociodemográficos e hospitalares com o nível de ansiedade que apresentam os familiares com pacientes hospitalizados na Unidade de Cuidados Intensivos Pediátricos (UCIP). Metodologia: Estudo Quantitativo, descritivo e transversal. Utilizou-se um instrumento de elaboração própria para a identificação de fatores sociodemográficos e hospitalares; e a escala de Inventário de Ansiedade Estado-Traço de Spielberger (IDARE) para a medição do nível de ansiedade. Resultados: 34 familiares participaram, 11.8% (4) homens e 88.2% (30) mulheres, a média da idade foi de 29 anos, as pontuações de ansiedade estado e ansiedade traço, indicam que quando conhecer algum abrigo se apresenta uma diferença significativa no nível de ansiedade estado dos familiares (X
Assuntos
Humanos , Masculino , FemininoAssuntos
Aortografia , Doenças Cardiovasculares/diagnóstico por imagem , Aorta Torácica/diagnóstico por imagem , Aneurisma Aórtico/diagnóstico por imagem , Síndromes do Arco Aórtico/diagnóstico por imagem , Coartação Aórtica/diagnóstico por imagem , Estenose da Valva Aórtica/diagnóstico por imagem , Cateterismo Cardíaco , Permeabilidade do Canal Arterial/diagnóstico por imagem , Humanos , MétodosAssuntos
Angina Pectoris/tratamento farmacológico , Teste de Esforço , Piperidinas/uso terapêutico , Vasodilatadores/uso terapêutico , Adulto , Aerobiose , Ensaios Clínicos como Assunto , Feminino , Frequência Cardíaca , Humanos , Masculino , Maleatos/uso terapêutico , Pessoa de Meia-Idade , Consumo de Oxigênio , Perexilina/uso terapêutico , Placebos , Fatores de TempoAssuntos
Angina Pectoris/tratamento farmacológico , Piperidinas/uso terapêutico , Vasodilatadores/uso terapêutico , Adulto , Idoso , Ensaios Clínicos como Assunto , Eletrocardiografia , Estudos de Avaliação como Assunto , Teste de Esforço , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Nitroglicerina/uso terapêutico , Tetranitrato de Pentaeritritol/uso terapêutico , Perexilina/uso terapêutico , Piperidinas/efeitos adversos , Vasodilatadores/efeitos adversos , Vertigem/induzido quimicamenteRESUMO
No disponible
Assuntos
Humanos , Consenso , Hipertensão/epidemiologia , Hipertensão/prevenção & controle , Doenças Cardiovasculares/complicações , Inibidores de Hidroximetilglutaril-CoA Redutases/uso terapêutico , Doenças Cardiovasculares/prevenção & controle , Saúde Holística/tendências , Estilo de VidaRESUMO
In a multicenter, open, noncomparative trial to assess the efficacy of an angiotensin-converting enzyme inhibitor, quinapril (Accupril; Parke-Davis), after 12 weeks of treatment in 667 adult patients 19-83 years of age with stage 1-3 hypertension, conducted by 85 physicians in primary health care, with systolic blood pressure (SBP) < 140 mm Hg and diastolic blood pressure (DBP) < 90 mm Hg as criteria for normalization, the efficacy of the drug was 75.1%. When an analysis was made of the frequency tables of BP recorded by the physicians in the case-report forms, a clear numerical preference was found in which the DBP was expressed in multiples of 5 in 81.3% of the cases and the SBP was expressed in multiples of 10 in 19% of the records, so that when a cutoff point <140/90 mm Hg is chosen in daily practice, 130/85 mm Hg is actually being selected. It suffices to change the criteria to accept as normal values less than or equal to instead of less than 140/90 mm Hg to increase the efficacy of the drug from 75.1% to 90.7% in our trial. Therefore, it is proposed to use multiples of 5 for DBP and multiples of 10 for SBP as cutoff points and the diffusion of clear recommendations on BP measurement.