Detalhe da pesquisa
1.
FTIR-based L-asparaginase activity assay enables continuous measurements in optically dense media including blood plasma.
Anal Biochem
; 598: 113694, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32217095
2.
Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes.
Biochem Biophys Res Commun
; 509(3): 790-796, 2019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30612734
3.
Murine regulatory T cells induce death of effector T, B, and NK lymphocytes through a contact-independent mechanism involving telomerase suppression and telomere-associated senescence.
Cell Immunol
; 331: 146-160, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29935763
4.
Rhodospirillum rubruml-asparaginase targets tumor growth by a dual mechanism involving telomerase inhibition.
Biochem Biophys Res Commun
; 492(2): 282-288, 2017 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28837806
5.
Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.
J Med Chem
; 64(15): 11432-11444, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34283610
6.
Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes.
Biochimie
; 174: 34-43, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315661
7.
Penetration into Cancer Cells via Clathrin-Dependent Mechanism Allows L-Asparaginase from Rhodospirillum rubrum to Inhibit Telomerase.
Pharmaceuticals (Basel)
; 13(10)2020 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33008089
8.
Endonuclease G modulates the alternative splicing of deoxyribonuclease 1 mRNA in human CD4+ T lymphocytes and prevents the progression of apoptosis.
Biochimie
; 157: 158-176, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30521874
9.
Contact-independent suppressive activity of regulatory T cells is associated with telomerase inhibition, telomere shortening and target lymphocyte apoptosis.
Mol Immunol
; 101: 229-244, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30025223
10.
Alternative splicing of telomerase catalytic subunit hTERT generated by apoptotic endonuclease EndoG induces human CD4+ T cell death.
Eur J Cell Biol
; 96(7): 653-664, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28886883
11.
Inhibition of telomerase activity and induction of apoptosis by Rhodospirillum rubrum L-asparaginase in cancer Jurkat cell line and normal human CD4+ T lymphocytes.
Cancer Med
; 6(11): 2697-2712, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28984046