RESUMO
AIM: To validate the Individualized Metabolic Surgery (IMS) score and assess long-term remission of type 2 diabetes (T2D) after duodenal switch (DS)-type procedures in patients with obesity. In addition, to help guide metabolic procedure selection for those patients categorized as having severe T2D. MATERIALS AND METHODS: This is a retrospective single cohort study of all patients with T2D and severe obesity, who underwent DS-type procedures at a single institution from December 2010 to December 2018. Study endpoints included validating the IMS score in our cohort and evaluating the impact of DS-type procedures on long-term (≥ 5 years) remission of T2D, especially in patients with severe disease. A receiver operator characteristic curve was used to assess the accuracy of the IMS score using the area under the curve (AUC). RESULTS: The study cohort included 30 patients with complete baseline and long-term glycaemic data after their index DS-type surgery. Twelve patients (40%) were classified with severe T2D, and the distribution of IMS-based severity groups was similar between our cohort and the original IMS study (P = .42). IMS scores predicted long-term T2D remission with AUC = 0.77. Patients with IMS-based severe diabetes achieved significantly higher long-term remission after DS-type procedures compared with gastric bypass and/or sleeve gastrectomy from the original IMS study (42% vs. 12%; P < .05). CONCLUSIONS: The IMS score properly classifies the severity of T2D in our study cohort and adequately predicts its long-term remission after DS-type procedures. While T2D remission decreases with more severe IMS scores, long-term remission remains high after DS-type procedures among patients with severe disease.
Assuntos
Diabetes Mellitus Tipo 2 , Duodeno , Obesidade Mórbida , Indução de Remissão , Humanos , Diabetes Mellitus Tipo 2/cirurgia , Diabetes Mellitus Tipo 2/complicações , Feminino , Masculino , Estudos Retrospectivos , Pessoa de Meia-Idade , Adulto , Obesidade Mórbida/cirurgia , Obesidade Mórbida/complicações , Obesidade Mórbida/metabolismo , Duodeno/cirurgia , Cirurgia Bariátrica/métodos , Resultado do TratamentoRESUMO
A 4-year-old boy, not known to have any medical illness, presented to several medical facilities reporting right upper quadrant and right flank pain, intermittent fever and chills for 3â months. A CT of the abdomen showed that a swallowed 'bobby pin' had pierced through the right kidney. This finding explained the boy's symptoms. The pin was removed by laparotomy without any subsequent complication. The patient had an uneventful postoperative recovery.