Detalhe da pesquisa
1.
Lipidomic-Based Approach to 10 s Classification of Major Pediatric Brain Cancer Types with Picosecond Infrared Laser Mass Spectrometry.
Anal Chem
; 96(3): 1019-1028, 2024 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38190738
2.
A Workflow for Meaningful Interpretation of Classification Results from Handheld Ambient Mass Spectrometry Analysis Probes.
Int J Mol Sci
; 25(6)2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38542461
3.
Metabolic Lipids in Melanoma Enable Rapid Determination of Actionable BRAF-V600E Mutation with Picosecond Infrared Laser Mass Spectrometry in 10 s.
Anal Chem
; 95(38): 14430-14439, 2023 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37695851
4.
An effective kinase inhibition strategy for metastatic recurrent childhood medulloblastoma.
J Neurooncol
; 163(3): 635-645, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37354357
5.
Picosecond Infrared Laser Mass Spectrometry Identifies a Metabolite Array for 10 s Diagnosis of Select Skin Cancer Types: A Proof-of-Concept Feasibility Study.
Anal Chem
; 94(48): 16821-16830, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36395434
6.
Functional characterization of a PROTAC directed against BRAF mutant V600E.
Nat Chem Biol
; 16(11): 1170-1178, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32778845
7.
A drug discovery platform to identify compounds that inhibit EGFR triple mutants.
Nat Chem Biol
; 16(5): 577-586, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32094923
8.
Mass Spectrometry Imaging Reveals a Gradient of Cancer-like Metabolic States in the Vicinity of Cancer Not Seen in Morphometric Margins from Microscopy.
Anal Chem
; 93(10): 4408-4416, 2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33651938
9.
(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells.
Proc Natl Acad Sci U S A
; 111(35): 12853-8, 2014 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25136132
10.
Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells.
Apoptosis
; 20(7): 948-59, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25832785
11.
Discovery of Conformationally Constrained ALK2 Inhibitors.
J Med Chem
; 67(6): 4707-4725, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38498998
12.
Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor.
ACS Med Chem Lett
; 14(2): 199-210, 2023 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36793435
13.
Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity.
Cell Chem Biol
; 30(7): 795-810.e8, 2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37369212
14.
L-745,870 reduces L-DOPA-induced dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.
J Pharmacol Exp Ther
; 342(2): 576-85, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22619253
15.
Combinatorial Anticancer Drug Screen Identifies Off-Target Effects of Epigenetic Chemical Probes.
ACS Chem Biol
; 17(10): 2801-2816, 2022 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36084291
16.
Erlotinib synergizes with the poly(ADP-ribose) glycohydrolase inhibitor ethacridine in acute myeloid leukemia cells.
Haematologica
; 101(11): e449-e453, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27587383
17.
Leveraging Open Science Drug Development for PET: Preliminary Neuroimaging of 11C-Labeled ALK2 Inhibitors.
ACS Med Chem Lett
; 12(5): 846-850, 2021 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34055235
18.
Structure-Activity Relationship of USP5 Inhibitors.
J Med Chem
; 64(20): 15017-15036, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34648286
19.
A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity.
JCI Insight
; 6(5)2021 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33476303
20.
Design, Synthesis, and Characterization of 4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma.
J Med Chem
; 64(15): 11129-11147, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34291633