Detalhe da pesquisa
1.
Trypanosoma brucei Invariant Surface gp65 Inhibits the Alternative Pathway of Complement by Accelerating C3b Degradation.
J Immunol
; 211(5): 862-873, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37466368
2.
Bispecific Complement Engagers for Targeted Complement Activation.
J Immunol
; 211(3): 403-413, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37350633
3.
Novel homozygous CD46 variant with C-isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome.
Eur J Immunol
; 52(10): 1610-1619, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35987516
4.
Structural and functional analyses of antibodies specific for modified core N-glycans suggest a role in TH 2 responses.
Allergy
; 78(1): 121-130, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35726192
5.
Complement Receptor 3 Forms a Compact High-Affinity Complex with iC3b.
J Immunol
; 206(12): 3032-3042, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34117107
6.
Mutation-induced dimerization of transforming growth factor-ß-induced protein may drive protein aggregation in granular corneal dystrophy.
J Biol Chem
; 297(1): 100858, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34097874
7.
An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase.
J Immunol
; 205(6): 1678-1694, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32769120
8.
A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
J Immunol
; 205(8): 2287-2300, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32938727
9.
A C3-specific nanobody that blocks all three activation pathways in the human and murine complement system.
J Biol Chem
; 295(26): 8746-8758, 2020 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32376685
10.
Functional and structural insight into properdin control of complement alternative pathway amplification.
EMBO J
; 36(8): 1084-1099, 2017 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28264884
11.
Structure of and influence of a tick complement inhibitor on human complement component 5.
Nat Immunol
; 9(7): 753-60, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18536718
12.
Structure of intact IgE and the mechanism of ligelizumab revealed by electron microscopy.
Allergy
; 75(8): 1956-1965, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32037590
13.
Structure and activation of C1, the complex initiating the classical pathway of the complement cascade.
Proc Natl Acad Sci U S A
; 114(5): 986-991, 2017 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28104818
14.
Structural insight into proteolytic activation and regulation of the complement system.
Immunol Rev
; 274(1): 59-73, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27782336
15.
Correction: A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.
J Biol Chem
; 299(2): 102951, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36739657
16.
A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.
J Biol Chem
; 293(17): 6269-6281, 2018 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29497000
17.
Complement activation, regulation, and molecular basis for complement-related diseases.
EMBO J
; 34(22): 2735-57, 2015 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26489954
18.
Maximizing Sequence Coverage in Top-Down Proteomics By Automated Multimodal Gas-Phase Protein Fragmentation.
Anal Chem
; 90(21): 12519-12526, 2018 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30252444
19.
Solution Structures of Complement C2 and Its C4 Complexes Propose Pathway-specific Mechanisms for Control and Activation of the Complement Proconvertases.
J Biol Chem
; 291(32): 16494-507, 2016 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27252379
20.
Structural Basis for Simvastatin Competitive Antagonism of Complement Receptor 3.
J Biol Chem
; 291(33): 16963-76, 2016 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27339893