Detalhe da pesquisa
1.
Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding.
Nucleic Acids Res
; 51(3): 1409-1423, 2023 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36124719
2.
Simultaneous inhibition of endocytic recycling and lysosomal fusion sensitizes cells and tissues to oligonucleotide therapeutics.
Nucleic Acids Res
; 51(4): 1583-1599, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36727438
3.
Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides.
Nucleic Acids Res
; 49(16): 9026-9041, 2021 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417625
4.
The Unexpected Base-Pairing Behavior of Cyanuric Acid in RNA and Ribose versus Cyanuric Acid Induced Helicene Assembly of Nucleic Acids: Implications for the Pre-RNA Paradigm.
Chemistry
; 27(12): 4033-4042, 2021 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33174270
5.
Nanopore Sequencing of an Expanded Genetic Alphabet Reveals High-Fidelity Replication of a Predominantly Hydrophobic Unnatural Base Pair.
J Am Chem Soc
; 142(5): 2110-2114, 2020 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31985216
6.
Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins.
J Am Chem Soc
; 142(16): 7456-7468, 2020 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32202774
7.
Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism.
J Am Chem Soc
; 141(27): 10644-10653, 2019 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31241334
8.
Perioperative and Periprocedural Care of Patients With Intrathecal Pump Therapy.
Neuromodulation
; 22(7): 775-780, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30378724
9.
Periprocedural Considerations for Patients with Gastric Electrical Stimulators.
Neuromodulation
; 22(6): 680-683, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31353795
10.
Heterogeneous Pyrophosphate-Linked DNA-Oligonucleotides: Aversion to DNA but Affinity for RNA.
Chemistry
; 24(26): 6837-6842, 2018 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29532524
11.
Naloxone Academic Detailing: Role of Community Outreach Teaching.
Curr Pain Headache Rep
; 22(11): 72, 2018 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30151695
12.
Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes.
Nucleic Acids Res
; 44(5): 2007-19, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26857548
13.
Merging Two Strategies for Mixed-Sequence Recognition of Double-Stranded DNA: Pseudocomplementary Invader Probes.
J Org Chem
; 81(8): 3335-46, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26998918
14.
Recognition of Double-Stranded DNA Using Energetically Activated Duplexes Modified with N2'-Pyrene-, Perylene-, or Coronene-Functionalized 2'-N-Methyl-2'-amino-DNA Monomers.
J Org Chem
; 80(11): 5395-406, 2015 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25984765
15.
Synthesis and characterization of oligodeoxyribonucleotides modified with 2'-thio-2'-deoxy-2'-S-(pyren-1-yl)methyluridine.
Bioorg Med Chem Lett
; 25(18): 3999-4004, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26254942
16.
Mixed-Sequence Recognition of Double-Stranded DNA Using Enzymatically Stable Phosphorothioate Invader Probes.
Molecules
; 20(8): 13780-93, 2015 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26230684
17.
Using a Systems Engineering Initiative for Patient Safety to Evaluate a Hospital-wide Daily Chlorhexidine Bathing Intervention.
J Nurs Care Qual
; 30(4): 337-44, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26035708
18.
Targeted metabolomics of Physaria fendleri, an industrial crop producing hydroxy fatty acids.
Plant Cell Physiol
; 55(3): 620-33, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24443498
19.
C5-alkynyl-functionalized α-L-LNA: synthesis, thermal denaturation experiments and enzymatic stability.
J Org Chem
; 79(11): 5062-73, 2014 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24797769
20.
Synthesis and biophysical properties of C5-functionalized LNA (locked nucleic acid).
J Org Chem
; 79(11): 5047-61, 2014 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24825249