Detalhe da pesquisa
1.
PCSK9 rs11591147 R46L loss-of-function variant protects against liver damage in individuals with NAFLD.
Liver Int
; 41(2): 321-332, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33091218
2.
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD).
Nat Metab
; 2024 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38867022
3.
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis.
Elife
; 122023 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36648330
4.
Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.
Diabetes
; 72(10): 1350-1363, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36580483
5.
Inhibition of SGLT2 Preserves Function and Promotes Proliferation of Human Islets Cells In Vivo in Diabetic Mice.
Biomedicines
; 10(2)2022 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35203411
6.
Hepatic patatin-like phospholipase domain-containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans.
Hepatol Commun
; 6(10): 2689-2701, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35833455
7.
PSD3 downregulation confers protection against fatty liver disease.
Nat Metab
; 4(1): 60-75, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35102341
8.
TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis.
Nat Commun
; 13(1): 6020, 2022 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36241646
9.
The APOE∗3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis.
J Diabetes Res
; 2019: 9727952, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30949516
10.
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice.
Mol Metab
; 22: 49-61, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30772256
11.
Modeling human pancreatic beta cell dedifferentiation.
Mol Metab
; 10: 74-86, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29472102
12.
Hyperglycemia Induced by Glucokinase Deficiency Accelerates Atherosclerosis Development and Impairs Lesion Regression in Combined Heterozygous Glucokinase and the Apolipoprotein E-Knockout Mice.
J Diabetes Res
; 2016: 8630961, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27774459
13.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
; 24(4): 593-607, 2016 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27667667
14.
Confocal scanning laser microscopy measurements of atherosclerotic lesions in mice aorta. A fast evaluation method for volume determinations.
Atherosclerosis
; 179(1): 35-42, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15721007
15.
GPR55 deletion in mice leads to age-related ventricular dysfunction and impaired adrenoceptor-mediated inotropic responses.
PLoS One
; 9(9): e108999, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25275556