Detalhe da pesquisa
1.
Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand.
Genome Res
; 27(8): 1336-1343, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28512192
2.
APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context.
Genome Res
; 27(2): 175-184, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27940951
3.
Germline PMS2 and somatic POLE exonuclease mutations cause hypermutability of the leading DNA strand in biallelic mismatch repair deficiency syndrome brain tumours.
J Pathol
; 243(3): 331-341, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28805995
4.
Discovery of recessive effect of human polymerase δ proofreading deficiency through mutational analysis of POLD1-mutated normal and cancer cells.
Eur J Hum Genet
; 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38658779
5.
Error-prone bypass of DNA lesions during lagging-strand replication is a common source of germline and cancer mutations.
Nat Genet
; 51(1): 36-41, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30510240
6.
Are Nonsense Alleles of Drosophila melanogaster Genes under Any Selection?
Genome Biol Evol
; 10(4): 1012-1018, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29425311
7.
Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma.
Nat Genet
; 48(4): 398-406, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26950094