Detalhe da pesquisa
1.
Formation of A Novel Purine Metabolite through CYP3A4 Bioactivation and Glutathione Conjugation.
Drug Metab Lett
; 10(2): 144-50, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27165340
2.
Application of 1D and 2D 1H-NMR in the structural elucidation of a N-glucuronidated metabolite and oxidized metabolites generated in microsomal incubation.
Drug Metab Lett
; 6(4): 265-74, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23607719
3.
Discovery of highly potent and selective pan-Aurora kinase inhibitors with enhanced in vivo antitumor therapeutic index.
J Med Chem
; 55(7): 3250-60, 2012 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22380736
4.
Identification of 1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride (CEP-32496), a highly potent and orally efficacious inhibitor of V-RAF murine sarcoma viral oncogene homologue B1 (BRAF) V600E.
J Med Chem
; 55(3): 1082-105, 2012 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22168626
5.
CEP-32496: a novel orally active BRAF(V600E) inhibitor with selective cellular and in vivo antitumor activity.
Mol Cancer Ther
; 11(4): 930-41, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22319199
6.
Characterization of a metalloregulatory bismuth(III) site in Staphylococcus aureus pI258 CadC repressor.
J Biol Inorg Chem
; 7(4-5): 551-9, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11941514
7.
Ratiometric pulsed alkylation mass spectrometry as a probe of thiolate reactivity in different metalloderivatives of Staphylococcus aureus pI258 CadC.
Biochemistry
; 43(13): 3824-34, 2004 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15049689