Night work is related to higher global and central adiposity in Brazil: National Health Survey, 2013.

BACKGROUND: Night work can disturb the natural circadian rhythm, leading to disruptions in metabolic rate and subsequent overall gain weight or even more harmful abdominal adiposity. Our aims were to investigate the associations between night work frequency and markers of overall and central obesity. METHODS: We conducted a cross-sectional analysis of data from the Brazilian National Health Survey on over 35 500 current workers. Exposure to current night work was composed of three categories: daytime work (reference category), less than one night per week, and more than two nights per week. The body mass index and waist circumference were used as adiposity markers. Logistic and multinomial regression models were used, with adjustment for demographic characteristics, work conditions, self-related health, and health-related behaviors. RESULTS: After complete adjustment, individuals who worked two or more nights a week had higher odds of overweight (odds ratio [OR]: 1.20, 95% CI: 1.04-1.38), obesity (OR: 1.38, 95% CI: 1.17-1.64) and increased waist circumference (OR: 1.27, 95% CI: 1.10-1.46) than daytime workers. CONCLUSIONS: Night work was significantly associated with measures of adiposity. Changes in working conditions, such as controlling the numbers of nights worked per week or promoting workplaces with healthy meals and the opportunity to perform physical exercise at work, could be suggested.

Shift work, job strain, and metabolic syndrome: Cross-sectional analysis of ELSA-Brasil.

BACKGROUND: Shift work and psychosocial stressors may contribute to higher metabolic syndrome (MetS) incidence. Few studies investigated whether the presence of both factors simultaneously has a synergic effect on risk of MetS. METHODS: This cross-sectional analysis used baseline data (2008-2010) for 10 960 current workers from ELSA-Brasil. Multiple logistic regression was used to estimate independent associations between shift work and job strain and MetS. An interaction between these factors was tested by including a multiplicative term in the final model. RESULTS: Exposure to three-shifts a week (that is, three 12 h shifts of work followed by 36 h of rest) and high job-strain were independently associated with greater risk of MetS. We found no indication (P > 0.05) of interaction between working in shifts and job strain on MetS. CONCLUSIONS: Efforts to reduce job strain and shift work should be considered as part of a primary prevention strategy to reduce the risk of MetS.

Association between diabetes and cognitive function at baseline in the Brazilian Longitudinal Study of Adult Health (ELSA- Brasil).

Diabetes has been associated with cognitive changes and an increased risk of vascular dementia and Alzheimer's disease, but it is unclear whether there are associations between diabetes and early alterations in cognitive performance. The present study consisted of a cross-section analysis of 14,444 participants aged 35-74 years and from a developing country at baseline in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil); these participants were recruited between 2008 and 2010. We investigated whether there was an association between diabetes and early changes in the cognitive performance of this Brazilian population. To assess cognitive domains, we used the word-list learning, word-list delayed recall and word recognition tests along. Phonemic verbal fluency tests included semantic phonemic test (animals) and a phonemic test (words beginning with the letter F). Executive functions associated with attention, concentration and psychomotor speed were evaluated using the Trail Making Test B. The exposure variable in the study was defined as diabetes. Multiple linear regression was used to estimate the association between diabetes and cognitive performance. The results were adjusted for age, sex, education, hypertension, coronary disease, depression, physical activity, smoking, alcohol consumption, and the cholesterol/HDL-C ratio. We found a significant association between diabetes and decreased memory, language and executive function (attention, concentration and psychomotor speed) performance in this population from a country with a distinct epidemiological profile, even after adjusting for the main intervening variables.

Relation of Thoracic Aortic and Coronary Artery Calcium to Cardiovascular Risk Factors (from The Brazilian Longitudinal Study of Adult Health [ELSA-Brazil]).

Thoracic aortic calcium (TAC) and coronary artery calcium (CAC) are associated with an increased risk of cardiovascular disease (CVD) and death. However, risk factors associated with arterial calcium may vary across vascular beds. We verified whether TAC is associated with the same risk factors as is CAC in adults without established CVD. Cross-sectional analysis including 2,433 participants (aged 38 to 78 years) of ELSA-Brasil cohort in Minas Gerais, Brazil. Nonenhanced ECG-gated multislice computed tomography were performed to detect calcium in the thoracic aorta and the coronaries (2015 to 2016). Multivariate logistic regression evaluated the associations of both TAC and CAC with CVD risk factors (smoking, body mass index, physical activity, alcohol intake, family history of CVD, low-density lipoprotein- and high-density lipoprotein-cholesterol, HbA1c, blood pressure, antidiabetic, antihypertensive, and lipid lowering medications). Overall prevalence of TAC and CAC were 69% and 43%, respectively. CAC prevalence was lower among women (31%) than men (56%) (Adjusted odds ratio [OR] 0.30; 0.24 to 0.38). After adjustments, black individuals were less likely to have any CAC as compared with whites (OR 0.63; 0.47 to 0.86). Neither sex, nor race/skin color were statistically associated with TAC. Use of antidiabetic medications remained associated with CAC (OR 1.80; 1.23 to 2.631.01), but not with TAC. All other risk factors, except education, alcohol, physical activity and HbA1c, persisted statistically associated with both TAC and CAC in the final analysis, with small differences in the magnitudes of the ORs. In conclusion, the only disagreements seen in the risk factors associated with CAC and TAC were sex, race/skin color, and use of antidiabetic medications.