Detalhe da pesquisa
1.
Novel quinazolin-4(3H)-one based Cyclin K degraders regulate alternative polyadenylation activity.
Biochem Biophys Res Commun
; 676: 6-12, 2023 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37480690
2.
Gene regulatory network analysis defines transcriptome landscape with alternative splicing of human umbilical vein endothelial cells during replicative senescence.
BMC Genomics
; 22(1): 869, 2021 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34856941
3.
Identification of a selective DDX3X inhibitor with newly developed quantitative high-throughput RNA helicase assays.
Biochem Biophys Res Commun
; 523(3): 795-801, 2020 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31954521
4.
The RNA helicase DDX39B and its paralog DDX39A regulate androgen receptor splice variant AR-V7 generation.
Biochem Biophys Res Commun
; 483(1): 271-276, 2017 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28025139
5.
Targeting pre-mRNA splicing in cancers: roles, inhibitors, and therapeutic opportunities.
Front Oncol
; 13: 1152087, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37342192
6.
Sbp2l contributes to oligodendrocyte maturation through translational control in Tcf7l2 signaling.
iScience
; 26(12): 108451, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38213786
7.
Secretory co-factors in next-generation cellular therapies for cancer.
Front Immunol
; 13: 907022, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36059449
8.
Synergistic apoptotic effects in cancer cells by the combination of CLK and Bcl-2 family inhibitors.
PLoS One
; 15(10): e0240718, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33064779
9.
Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation.
Commun Biol
; 2: 165, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31069274
10.
Decoding Transcriptome Dynamics of Genome-Encoded Polyadenylation and Autoregulation with Small-Molecule Modulators of Alternative Polyadenylation.
Cell Chem Biol
; 25(12): 1470-1484.e5, 2018 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30293940
11.
Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors.
J Med Chem
; 61(17): 7710-7728, 2018 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30067358
12.
CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor.
Nat Commun
; 8(1): 7, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28232751
13.
Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing.
PLoS One
; 10(1): e0116929, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25581376
14.
DNase γ is the effector endonuclease for internucleosomal DNA fragmentation in necrosis.
PLoS One
; 8(12): e80223, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24312463
15.
Biomarkers for predicting the sensitivity of cancer cells to TRAIL-R1 agonistic monoclonal antibody.
Cancer Lett
; 292(2): 269-79, 2010 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20056315
16.
Possible contribution of DNase gamma to immunoglobulin V gene diversification.
Immunol Lett
; 125(1): 22-30, 2009 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19501119
17.
DNase gamma-dependent and -independent apoptotic DNA fragmentations in Ramos Burkitt's lymphoma cell line.
Biomed Res
; 30(3): 165-70, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19574717
18.
Action of apoptotic endonuclease DNase gamma on naked DNA and chromatin substrates.
Biochem Biophys Res Commun
; 345(2): 560-7, 2006 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-16690030
19.
RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation.
J Biol Chem
; 277(44): 41423-7, 2002 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12205088