Detalhe da pesquisa
1.
Surprising Reactivity in NiXantphos/Palladium-Catalyzed α-Arylation of Substituted Cyclopropyl Nitriles.
J Org Chem
; 84(8): 4670-4679, 2019 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30412410
2.
Branched/linear selectivity in palladium-catalyzed allyl-allyl cross-couplings: The role of ligands.
Tetrahedron
; 71(37): 6409-6413, 2015 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26279591
3.
Congested C-C bonds by Pd-catalyzed enantioselective allyl-allyl cross-coupling, a mechanism-guided solution.
J Am Chem Soc
; 136(19): 7092-100, 2014 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24720611
4.
Stereocontrol in Palladium-Catalyzed Propargylic Substitutions: Kinetic Resolution to give Enantioenriched 1,5-Enynes and Propargyl Acetates.
Adv Synth Catal
; 355(17): 3413-3419, 2013 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24839434
5.
Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson's Disease.
J Med Chem
; 66(21): 14912-14927, 2023 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37861679
6.
Construction of 1,5-enynes by stereospecific Pd-catalyzed allyl-propargyl cross-couplings.
J Am Chem Soc
; 134(21): 8770-3, 2012 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22594398
7.
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease.
J Med Chem
; 65(24): 16801-16817, 2022 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36475697
8.
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors.
J Med Chem
; 65(1): 838-856, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34967623
9.
Diastereocontrol in asymmetric allyl-allyl cross-coupling: stereocontrolled reaction of prochiral allylboronates with prochiral allyl chlorides.
J Am Chem Soc
; 133(42): 16778-81, 2011 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21973180
10.
Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors.
RSC Med Chem
; 12(7): 1164-1173, 2021 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34355182
11.
Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy.
ACS Med Chem Lett
; 10(11): 1530-1536, 2019 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31749906