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1.
BMC Med Ethics ; 24(1): 79, 2023 10 04.
Artigo em Inglês | MEDLINE | ID: mdl-37794440

RESUMO

BACKGROUND: Healthcare professionals use the ethics of justice and care to construct moral reasoning. These ethics are conflicting in nature; different value systems and orders of justice and care are applied to the cause of actual moral conflict. We aim to clarify the structure and factors of healthcare professionals' moral conflicts through the lens of justice and care to obtain suggestions for conflict resolutions. METHOD: Semi-structured interviews about experiences of moral conflict were conducted with Japanese nurses recruited using the snowball sampling method. Interviews were conducted based on the real-life moral conflict and choice interview. Interviews were recorded and transcribed verbatim, then analyzed based on the interpretive method of data analysis. Verbatim transcripts were read four times, first to get an overall sense of the conflict, then to understand the person's thoughts and actions that explain the conflict, and third and fourth to identify perspectives of justice and care, respectively. Each moral perspective was classified into categories according to Chally's taxonomy. RESULTS: Among 31 responses, 2 that did not mention moral conflict were excluded, leaving 29 responses that were analyzed. These responses were classified into six cases with conflict between both justice and care perspectives or within one perspective, and into two cases without conflict between perspectives. The "rules" category of justice and the "welfare of others" category of care were included in many cases of conflict between two perspectives, and they frequently occurred in each perspective. CONCLUSIONS: The nurses in this study suggest that they make moral judgments based on moral values that are intertwined with justice and care perspectives complex manner.Organizational, professional, and patient-related factors influenced conflicts between justice and care. Additionally, multiple overlapping loyalties created conflicts within justice perspectives, and multifaceted aspects of care-provider's responsibility and patient need created conflicts within care. Decision-making biased towards one perspective can be distorted. It is important to consider ethical issues from both perspectives to resolve conflicts, especially the effective use of the ethics of care is recommended.


Assuntos
População do Leste Asiático , Princípios Morais , Enfermeiras e Enfermeiros , Humanos , Julgamento , Justiça Social , Enfermeiras e Enfermeiros/psicologia
2.
BMC Med Ethics ; 24(1): 5, 2023 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-36726120

RESUMO

BACKGROUND: No laws or official guidelines govern voluntary assisted dying (VAD) in Japan. A legislative bill on the termination of life-sustaining measures has yet to be sent to deliberations for legislation, due to strong opposition that has prevented it from being submitted to the Diet. However, Japan has recently witnessed several cases involving VAD. MAIN TEXT: Against this backdrop, we argue that Japan should begin discussion on VAD legislation, referring to the Voluntary Assisted Dying Act 2017 (VADA2017), which was established in 2017 in Victoria, Australia. VADA2017 puts in place a wide range of stringent safeguards and is considered worldwide to be the safest and most conservative policy on a physician offering assisted dying based on the patient's premeditated request. We consider what opposing opinions from society would arise in response to the VADA2017. Among these will include arguments against VAD itself, those against the validation of this act, and opinions that oppose even the initiation of the dialogue on VAD. CONCLUSIONS: We conclude that to protect the right to life among those placed in vulnerable positions and, at the same time, to respect decision-making of those who wish for immediate death due to unbearable suffering, the dialogue must immediately begin with that on introducing a policy more conservative than that of the VADA2017, which solidly considers arguments against VAD.


Assuntos
Médicos , Suicídio Assistido , Humanos , Japão , Vitória , Dissidências e Disputas
3.
BMC Endocr Disord ; 22(1): 40, 2022 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-35164727

RESUMO

BACKGROUND: Few epidemiological studies have been performed to clarify the association between glucose metabolism disorders in early adults (20 years old) and physiological and environmental factors, including body mass index (BMI) in junior high school days. Therefore, we examined the association between hemoglobin A1c (HbA1c) level and body size (BMI) in early adulthood and lifestyles, including sleep habits and BMI in junior high school days in Shika town, a small town in Japan, by conducting a retrospective cohort study. METHODS: We examined the HbA1c levels and body size (BMI) of 99 early adults who turned 20 years old between 2016 and 2020 and were residing in Shika town, Ishikawa Prefecture. We obtained the information on lifestyles and living environment factors, including BMI, from a questionnaire survey conducted among the subjects during their junior high school days (13-15 years old) from 2009 to 2013. RESULTS: No correlations were observed between the HbA1c levels and the BMI values of the early adults. A two-way analysis of covariance (with the HbA1c levels and BMI values of the early adults as main factors) of the body size and lifestyle habits of the junior high school students revealed that "sleep quality in junior high school" was significantly poorer in the high HbA1c group than in the low HbA1c group in the early adults with high BMI values only. This result was also supported by the logistic regression analysis result. CONCLUSIONS: The present results indicate that poor sleep quality in junior high school was associated with the high HbA1c levels of the early adults with higher BMI values, which suggests that good sleep quality in junior high school prevents the development of hyperglycemia. However, the present study did not find any relationship between early-adult BMI and HbA1c level.


Assuntos
Índice de Massa Corporal , Hemoglobinas Glicadas/análise , Qualidade do Sono , Feminino , Humanos , Japão , Masculino , Estudos Retrospectivos , Fatores de Risco , Adulto Jovem
4.
Bioethics ; 35(1): 40-46, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-32940374

RESUMO

In many countries, prenatal testing for certain fetal abnormalities is offered via publicly funded screening programs. The concept of reproductive autonomy is regarded as providing a justificatory basis for many such programs. The purpose of this study is to re-examine the normative basis of public prenatal screening for fetal abnormalities by changing our perspective from that of autonomy to obligation. After clarifying the understanding of autonomy adopted in the justification for public prenatal screening programs, we identify two problems concerning this justification: first, the extent to which the government is obliged to meet this demand is not evident; and, second, it is not clear whether the provision of public screening is the most appropriate way to promote autonomy. Next, to tackle these problems, we focus on Onora O'Neill's argument of rights and obligations. Drawing on this argument, we show that, in addressing the problems above, it is important to change our normative perspective from rights or autonomy to obligation. Our argument will show that since the government does not have an incontrovertibly fundamental obligation to promote autonomy, this obligation needs to be constrained in terms of compatibility with other fundamental obligations. In addition, even if a government is obliged to promote autonomy to some degree, there could be more appropriate means to achieve it than providing public prenatal screening; therefore, it is not necessary for government obligations to extend to the provision of public prenatal screening.


Assuntos
Autonomia Pessoal , Diagnóstico Pré-Natal , Dissidências e Disputas , Feminino , Governo , Humanos , Programas de Rastreamento , Gravidez
5.
BMC Med Ethics ; 22(1): 5, 2021 01 13.
Artigo em Inglês | MEDLINE | ID: mdl-33435976

RESUMO

BACKGROUND: In the coming years, surrogate decision-making is expected to become highly prevalent in Japanese clinical practice. Further, there has been a recent increase in activities promoting advance care planning, which potentially affects the manner in which judgements are made by surrogate decision-makers. This study aims to clarify the grounds on which surrogate decision-makers in Japan base their judgements. METHODS: In this qualitative study, semi-structured interviews were conducted to examine the judgement grounds in surrogate decision-making for critical life-sustaining treatment choices in acute care hospitals. RESULTS: A total of 228 participants satisfied the inclusion criteria, and 15 were selected for interviews. We qualitatively analysed the content of 14 interview transcripts, excluding one that did not meet the inclusion criteria. Based on this analysis, we extracted 4 core categories, 17 categories, 35 subcategories, and 55 codes regarding judgement grounds in surrogate decision-making. The four core categories were as follows: patient preference-oriented factor (Type 1), patient interest-oriented factor (Type 2), family preference-oriented factor (Type 3), and balanced patient/family preference-oriented factor (Type 4). The Type 4 core category represented attempts to balance the preferences of the patient with those of the surrogate decision-maker. CONCLUSIONS: Surrogate decision-makers based their decisions on important aspects related to a patient's life, and they considered not only the patient's preferences and best interests but also their own preferences. As the need for surrogate decisions will increase in the future, decision-makers will need to consider judgement grounds from a more diverse perspective.


Assuntos
Planejamento Antecipado de Cuidados , Tomada de Decisões , Humanos , Japão , Preferência do Paciente , Inquéritos e Questionários
6.
Sci Eng Ethics ; 26(6): 3249-3270, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-33048327

RESUMO

To consider whether or not we should aim to create a perfect healthy utopia on Earth, we focus on the SF novel Harmony (2008), written by Japanese writer Project Ito, and analyze various issues in the world established in the novel from a bioethical standpoint. In the world depicted in Harmony, preserving health and life is a top priority. Super-medicine is realized through highly advanced medical technologies. Citizens in Harmony are required to strictly control themselves to achieve perfect health and must always disclose their health information to the public and continuously prove their health. From a bioethical standpoint, the world in Harmony is governed by a "healthy longevity supremacy" principle, with being healthy equated to being good and right. Privacy no longer exists, as it is perceived ethical for citizens to openly communicate health-related information to establish one's credibility. Moreover, there is no room for self-determination concerning healthcare because medical interventions and care are completely routinized, automated, centralized, and instantly provided. This is a situation where the community exhibits extremely powerful and effective paternalism. One can argue that healthy longevity is highly preferred. But is it right to aim for a perfectly healthy society at all costs? Should we sacrifice freedom, privacy, vivid feelings, and personal dignity to achieve such a world? In our view, the answer is no, as this would require the loss of many essential values. We conclude by proposing an alternative governing principle for future healthcare, and refer to it as the "do-everything-in-moderation" principle.


Assuntos
Atenção à Saúde , Utopias , Liberdade , Nível de Saúde , Humanos , Privacidade
7.
Med Health Care Philos ; 22(1): 85-94, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29845419

RESUMO

The global increase in patients with chronic conditions has led to increased interest in ethical issues regarding such conditions. A basic biomedical principle-respect for autonomy-is being reexamined more critically in its clinical implications. New accounts of this basic principle are being proposed. While new accounts of respect for autonomy do underpin the design of many public programs and policies worldwide, addressing both chronic disease management and health promotion, the risk of applying such new accounts to clinical setting remain understudied. However, the application of new accounts of respect for autonomy to clinical settings could support disrespectful attitudes toward or undue interference with patients with chronic conditions. Reconsidering autonomy and respect using Kantian accounts, this paper proposes respect for persons as an alternative basic bioethical principle to respect for autonomy. Unlike the principle of respect for persons in the Belmont Report, our principle involves respecting any patient's decisions, behaviors, emotions, or life-style regardless of his or her "autonomous" capabilities. Thus, attitudes toward patients should be no different irrespective of the assessment of their decisional or executive capabilities.


Assuntos
Doença Crônica/psicologia , Direitos do Paciente , Autonomia Pessoal , Filosofia Médica , Ética Médica , Humanos , Defesa do Paciente
9.
BMC Med Ethics ; 19(1): 12, 2018 02 27.
Artigo em Inglês | MEDLINE | ID: mdl-29482542

RESUMO

BACKGROUND: Destination therapy (DT) is the permanent implantation of a left ventricular assist device (LVAD) in patients with end-stage, severe heart failure who are ineligible for heart transplantation. DT improves both the quality of life and prognosis of patients with end-stage heart failure. However, there are also downsides to DT such as life-threatening complications and the potential for the patient to live beyond their desired length of life following such major complications. Because of deeply ingrained cultural and religious beliefs regarding death and the sanctity of life, Japanese society may not be ready to make changes needed to enable patients to have LVADs deactivated under certain circumstances to avoid needless suffering. MAIN TEXT: Western ethical views that permit LVAD deactivation based mainly on respect for autonomy and dignity have not been accepted thus far in Japan and are unlikely to be accepted, given the current Japanese culture and traditional values. Some healthcare professionals might regard patients as ineligible for DT unless they have prepared advance directives. If this were to happen, the right to prepare an advance directive would instead become an obligation to do so. Furthermore, patient selection for DT poses another ethical issue. Given the predominant sanctity of life principle and lack of cost-consciousness regarding medical expenses, medically appropriate exclusion criteria would be ignored and DT could be applied to various patients, including very old patients, the demented, or even patients in persistent vegetative states, through on-site judgment. CONCLUSION: There is an urgent need for Japan to establish and enact a basic act for patient rights. The act should include: respect for a patient's right to self-determination; the right to refuse unwanted treatment; the right to prepare legally binding advance directives; the right to decline to prepare such directives; and access to nationally insured healthcare. It should enable those concerned with patient care involving DT to seek ethical advice from ethics committees. Furthermore, it should state that healthcare professionals involved in the discontinuation of life support in a proper manner are immune to any legal action and that they have the right to conscientiously object to LVAD deactivation.


Assuntos
Temas Bioéticos , Ética Médica , Acessibilidade aos Serviços de Saúde/ética , Insuficiência Cardíaca/terapia , Coração Auxiliar/ética , Qualidade de Vida , Tecnologia/ética , Diretivas Antecipadas , Análise Custo-Benefício , Cultura , Insuficiência Cardíaca/cirurgia , Transplante de Coração , Humanos , Japão , Cuidados Paliativos , Direitos do Paciente , Seleção de Pacientes , Autonomia Pessoal , Pessoalidade , Políticas , Estresse Psicológico , Valor da Vida
10.
Nihon Ronen Igakkai Zasshi ; 55(1): 98-105, 2018.
Artigo em Japonês | MEDLINE | ID: mdl-29503374

RESUMO

AIM: We developed quality-of-life (QOL) scales for patients receiving home medical care. The objective of this study was to examine the agreement between the scores of the scales answered by patients and those answered by their proxy, as cognitive decline may interfere with one's ability to understand complex topics, such as the QOL. METHODS: Participants were pairs of patients receiving home medical care and their proxy. The patients were asked to complete self-reported QOL scales (QOL-HC), and their proxies were asked to complete proxy-reported versions of the QOL scales (QOL-HC for caregivers). We then statistically examined the extent of agreement between the self- and proxy-reported QOL-HC scores using contingency tables and Spearman's rank correlation coefficient. The SPSS software program, version 24, was used for all statistical analyses. RESULTS: The concordance rate between patients and caregivers for questions 1 ( "Do you have peace of mind?" ), 2 ( "Do you feel satisfied with your life when you reflect on it?" ), 3 ( "Do you have someone that you spend time talking with?" ), and 4 ( "Are you satisfied with the home care service system?" ) were 52.3%, 52.3%, 79.5%, and 81.8%, respectively. The total scores for the patients and caregivers were significantly correlated (Spearman's ρ=0.364*). CONCLUSIONS: We created the first QOL scale for patients receiving home-based medical care and for caregivers. The findings of this study suggest that the QOL-HC can be used in clinical practice for the assessment of patients receiving professional home care.


Assuntos
Serviços de Assistência Domiciliar , Qualidade de Vida , Idoso , Idoso de 80 Anos ou mais , Demência/terapia , Feminino , Humanos , Masculino , Procurador , Autorrelato
11.
BMC Emerg Med ; 17(1): 23, 2017 07 14.
Artigo em Inglês | MEDLINE | ID: mdl-28709409

RESUMO

BACKGROUND: Medical care is obviously an important public service to ensure the health of a nation; however, medical resources are not always used appropriately. 'Convenience-store consultations' and inappropriate ambulance transportation represent instances of such improper use by contemporary Japanese citizens in recent years. This article illustrates two examples of misuse and discusses potential countermeasures by considering factors contributing to these behaviours. MAIN BODY: From both public and medical perspectives, these patient behaviours are problematic, causing potential harm to others, negative consequences to such patients themselves, exhaustion of healthcare staff, and breakdown of emergency medical services. Although citizens need to recognize the public nature and scarcity of medical care, the more immediate need may be to identify and to remove personal and social causes inducing such misuse. In addition, healthcare professionals should become more trustworthy. To combat these issues, one-sided penalties such as accusations or sanctions for patients who misuse the system cannot be justified in principle. If measures taken to prevent misuse are ineffective, imposing surcharges or restricting consultations may be considered official policy, but these are not acceptable for several reasons. CONCLUSION: For now, we conclude that we must rely on the spontaneous motivation of patients who engage in 'convenience-store consultations' and ambulance transportation instead of taking a taxi.


Assuntos
Serviços Médicos de Emergência/estatística & dados numéricos , Serviço Hospitalar de Emergência/estatística & dados numéricos , Mau Uso de Serviços de Saúde , Ambulâncias/estatística & dados numéricos , Humanos , Japão
12.
J Med Ethics ; 42(8): 524-7, 2016 08.
Artigo em Inglês | MEDLINE | ID: mdl-27099362

RESUMO

The Japanese government has asserted that the purpose of scientific activities is to search for the truth about the world and contribute to public interest of the humanities and claimed that research misconduct should occur under no circumstances ever. The revealing of each new case of research misconduct leads to the establishment of investigation committees and research guidelines, as well as punishments for the transgressors. However, we wonder if Japanese researchers are receiving different messages that might undermine the purpose of the former messages. First, Japan's policies on science and technology have been created to comprise an integration of merit-based evaluations, principles of competition and a concentrated and unbalanced distribution of research funding, leading to decreases in ordinary research funding for the researchers and an increase in fierce research competition. Second, Japanese government and society as a whole continue to send the researchers messages such as 'Only results matter', 'Be No. 1 as a top priority' and 'All we need now is scientific progress'. Third, cultural peculiarities may explain some of the actions relevant to research misconducts currently noted in Japan. We argue that it is essential to re-examine and improve the governmental policies and evaluation methods for research achievements need to be more multifaceted. In order to have the researchers act according to ethics, it is essential for them to reaffirm their objectives for working in the fields of science and medicine and the importance of balancing their personal profit with the greater cause for entering into this field.


Assuntos
Pesquisa Biomédica , Ética em Pesquisa/educação , Fidelidade a Diretrizes , Pesquisadores/ética , Má Conduta Científica , Pesquisa Biomédica/ética , Pesquisa Biomédica/estatística & dados numéricos , Competência Cultural , Fidelidade a Diretrizes/ética , Guias como Assunto , Humanos , Japão/epidemiologia , Princípios Morais , Pesquisadores/educação , Má Conduta Científica/ética , Má Conduta Científica/estatística & dados numéricos
13.
Bioethics ; 30(7): 520-7, 2016 09.
Artigo em Inglês | MEDLINE | ID: mdl-26833626

RESUMO

A murder case that had some features in common with the Tarasoff case occurred in Sasebo City, Japan, in 2014. A 15-year-old high school girl was murdered and her 16-year-old classmate was arrested on suspicion of homicide. One and a half months before the murder, a psychiatrist who had been examining the girl called a prefectural child consultation centre to warn that she might commit murder, but he did not reveal her name, considering it his professional duty to keep it confidential. Article 134 of the Japanese Criminal Law states that doctors should not disclose patient information obtained in clinical practice without a legitimate reason, but the Japanese Supreme Court has not specified what constitutes a legitimate reason. Mass media and commentators suggested that the murder could have been prevented if the psychiatrist had disclosed the girl's name to the authorities or had isolated her coercively in a psychiatric ward. However, the authors disagree with such claims. This article discusses obligations imposed on concerned individuals and third party members in cases involving ethical dilemmas regarding patient confidentiality and information disclosure. It is concluded that everyone should fulfill their obligations to prevent such tragedies and one should judge the appropriateness of others' actions based not on the consequences of their actions, but on the processes used to decide on a course of action and their commitment. It is necessary for us to establish a society in which concerned parties can do what they think is ethically best without fearing ungrounded charges.


Assuntos
Confidencialidade/ética , Responsabilidade pela Informação/ética , Obrigações Morais , Privacidade , Feminino , Homicídio , Humanos , Japão , Masculino
14.
BMC Med Ethics ; 15: 19, 2014 Mar 04.
Artigo em Inglês | MEDLINE | ID: mdl-24592932

RESUMO

BACKGROUND: Healthcare professionals must make decisions for patients based on ethical considerations. However, they rely on clinical ethics consultations (CEC) to review ethical justifications of their decisions. CEC consultants support the cases reviewed and guide medical care. When both healthcare professionals and CEC consultants face ethical problems in medical care, how is their judgment derived? How do medical judgments differ from the ethical considerations of CECs? This study examines CECs in Japan to identify differences in the ethical judgment of clients and CEC consultants. METHODS: The CEC request and response documents of all 60 cases reviewed across Japan between October 2006 and the end of October 2011 were classified in terms of the presence of decisional capacity in the patient. We conducted a qualitative content analysis of the differences in reasoning between client and CEC consultants. Reasoned judgments were verified in individual cases to classify the similarities or differences of opinion between CEC clients and teams. RESULTS: As the result of classification of the decisional capacity and the difference of opinion regarding medical care, the most frequent category was 25 cases (41.7%) of "uncertain decisional capacity," and 23 cases (38.3%) of "withholding of decision-making." A chi-square analysis was performed on presence of decisional capacity and agreement in decision-making, yielding a statistically significant difference (p < 0.05). The CEC consultants' reasoning was based on "patient's preference was ambiguous," "validity of family as a surrogate," "estimation of patient preference," and "patient's best interest," whereas the CEC client's reasoning was based on "consistent family preference was shown/not shown" and "appropriate therapeutic methods to manage patient safety." CONCLUSION: Differences in opinions were found in cases classified according to decisional capacity. Furthermore, the reasoning behind judgments differed between CEC clients and CEC consultants. The reasoning of CEC consultants was critical and reflective, while for clients it was situational and pragmatic.


Assuntos
Atitude do Pessoal de Saúde , Tomada de Decisões/ética , Comitês de Ética Clínica , Consultoria Ética , Ética em Pesquisa , Consentimento Livre e Esclarecido/ética , Assistência Terminal/ética , Ética Clínica , Feminino , Humanos , Japão , Masculino , Defesa do Paciente/ética , Relações Médico-Paciente , Qualidade da Assistência à Saúde , Qualidade de Vida
15.
BMC Med Ethics ; 15: 8, 2014 Feb 04.
Artigo em Inglês | MEDLINE | ID: mdl-24495473

RESUMO

BACKGROUND: Since Japan adopted the concept of informed consent from the West, its inappropriate acquisition from patients in the Japanese clinical setting has continued, due in part to cultural aspects. Here, we discuss the current status of and contemporary issues surrounding informed consent in Japan, and how these are influenced by Japanese culture. DISCUSSION: Current legal norms towards informed consent and information disclosure are obscure in Japan. For instance, physicians in Japan do not have a legal duty to inform patients of a cancer diagnosis. To gain a better understanding of these issues, we present five court decisions related to informed consent and information disclosure. We then discuss Japanese culture through reviews of published opinions and commentaries regarding how culture affects decision making and obtaining informed consent. We focus on two contemporary problems involving informed consent and relevant issues in clinical settings: the misuse of informed consent and persistence in obtaining consent. For the former issue, the phrase "informed consent" is often used to express an opportunity to disclose medical conditions and recommended treatment choices. The casual use of the expression "informed consent" likely reflects deep-rooted cultural influences. For the latter issue, physicians may try to obtain a signature by doing whatever it takes, lacking a deep understanding of important ethical principles, such as protecting human dignity, serving the patient's best interest, and doing no harm in decision-making for patients.There is clearly a misunderstanding of the concept of informed consent and a lack of complete understanding of ethical principles among Japanese healthcare professionals. Although similar in some respects to informed consent as it originated in the United States, our review makes it clear that informed consent in Japan has clear distinguishing features. SUMMARY: Japanese healthcare professionals should aim to understand the basic nature of informed consent, irrespective of their attitudes about individualism, liberalism, and patient self-determination. If they believe that the concept of informed consent is important and essential in Japanese clinical settings, efforts should be made to obtain informed consent in an appropriate manner.


Assuntos
Tomada de Decisões/ética , Consentimento Livre e Esclarecido/ética , Consentimento Livre e Esclarecido/legislação & jurisprudência , Legislação Médica , Direitos do Paciente , Médicos , Revelação da Verdade , Características Culturais , Revelação , Ética Médica , Feminino , Humanos , Japão/etnologia , Jurisprudência , Legislação Médica/ética , Legislação Médica/tendências , Masculino , Acesso dos Pacientes aos Registros , Defesa do Paciente , Direitos do Paciente/ética , Direitos do Paciente/legislação & jurisprudência , Pessoalidade , Relações Médico-Paciente , Medição de Risco , Revelação da Verdade/ética
16.
J Vet Med Sci ; 86(5): 493-496, 2024 May 06.
Artigo em Inglês | MEDLINE | ID: mdl-38538328

RESUMO

A 10-year-old American Shorthair cat presented with anorexia and jaundice, and echogenic evaluation revealed diffuse thickening of the common bile duct (CBD) wall. An exploratory laparotomy was conducted, the lesion was evaluated as difficult to remove, and the cat was euthanized and autopsied. Histologically, round neoplastic cells proliferated in the mucosa of the CBD and infiltrated the hepatic lobe, pancreas, and duodenum. Immunohistochemistry revealed that the neoplastic cells were positive for cytoplasmic-CD3 and granzyme B, and TCR-gamma clonal rearrangement was detected. Based on these findings, the neoplasia was diagnosed as a primary CBD lymphoma originating from cytotoxic T or natural killer cells. To the best of our knowledge, this is the first reported case of feline primary CBD lymphoma. Although rare, lymphoma of the CBD should be considered in cats with jaundice and thickening of the CBD.


Assuntos
Neoplasias dos Ductos Biliares , Doenças do Gato , Icterícia , Animais , Gatos , Neoplasias dos Ductos Biliares/veterinária , Neoplasias dos Ductos Biliares/patologia , Doenças do Gato/patologia , Doenças do Gato/diagnóstico , Ducto Colédoco/patologia , Icterícia/veterinária , Icterícia/etiologia , Linfoma/veterinária , Linfoma/patologia , Linfoma/complicações , Linfoma/diagnóstico
17.
Open Vet J ; 14(2): 743-749, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38549570

RESUMO

Background: Cardiac myxomas are benign tumours that can occur in any heart chamber or valve. They are extremely rare in dogs. We present a novel case involving a cardiac myxoma in the left ventricular outflow tract (LVOT) and a ventricular septal defect (VSD) in a small dog. Case Description: A female miniature dachshund (age, 7 months; weight, 2.88 kg) presented with growth insufficiency, lethargy, and a cardiac murmur. Echocardiography revealed a small polypoid mass in the LVOT and a membranous VSD. Simultaneous surgeries were performed to resect the mass (aortotomy) and close the VSD (right atriotomy) using low-flow cardiopulmonary bypass with surface-cooling hypothermia and retrograde cardioplegia. The tumour was histopathologically identified as a myxoma. The dog survived with no cardiac complications for 11 years after surgery. Conclusion: To our knowledge, this is the first report of ante-mortem diagnosis and simultaneous surgical repair of a cardiac myxoma obstructing the LVOT and a VSD in a small-breed dog. In addition to describing this complicated case, this report presents what we believe is the first reported use of retrograde cardioplegia during open-heart surgery in a small-breed dog.


Assuntos
Procedimentos Cirúrgicos Cardíacos , Doenças do Cão , Comunicação Interventricular , Mixoma , Obstrução da Via de Saída Ventricular Esquerda , Cães , Feminino , Animais , Obstrução da Via de Saída Ventricular Esquerda/veterinária , Comunicação Interventricular/complicações , Comunicação Interventricular/cirurgia , Comunicação Interventricular/veterinária , Ecocardiografia/veterinária , Procedimentos Cirúrgicos Cardíacos/veterinária , Mixoma/complicações , Mixoma/diagnóstico , Mixoma/cirurgia , Mixoma/veterinária , Doenças do Cão/diagnóstico , Doenças do Cão/cirurgia
18.
Bioethics ; 27(4): 186-93, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-22296589

RESUMO

A placebo is a substance or intervention believed to be inactive, but is administered by the healthcare professional as if it was an active medication. Unlike standard treatments, clinical use of placebo usually involves deception and is therefore ethically problematic. Our attitudes toward the clinical use of placebo, which inevitably includes deception or withholding information, have a tremendous effect on our practice regarding truth-telling and informed consent. A casual attitude towards it weakens the current practice based on shared decision-making and mutual trust between patients and healthcare professionals. Issues concerning the clinical use of placebo are thus intimately related to patient-provider relationships, the public's trust in medicine, and medical education. A review of recent survey studies suggests that the clinical use of placebo appears to be fairly well accepted among healthcare professionals and is common in clinical settings in various countries. However, we think that an ethical discussion is urgently needed because of its controversial nature. If judged to be ethically wrong, the practice should end. In the present paper, we discuss the ethicality of the clinical use of placebo with deception and argue against it, concluding that it is unethical and should be banned. We will show that most arguments in favor of the clinical use of placebo can be refuted and are therefore incorrect or weak. These arguments will be presented and examined individually. Finally, we will briefly consider issues relevant to the clinical use of placebo without deception.


Assuntos
Enganação , Ética Clínica , Placebos/uso terapêutico , Atitude do Pessoal de Saúde , Temas Bioéticos , Pessoal de Saúde/psicologia , Humanos , Consentimento Livre e Esclarecido
19.
BMC Med Ethics ; 14: 9, 2013 Feb 22.
Artigo em Inglês | MEDLINE | ID: mdl-23433312

RESUMO

BACKGROUND: A baby hatch called the "Stork's Cradle" has been in place at Jikei Hospital in Kumamoto City, Japan, since May 10, 2007. Babyklappes were first established in Germany in 2000, and there are currently more than 90 locations. Attitudes regarding baby hatches are divided in Japan and neither opinions for nor against baby hatches have thus far been overwhelming. To consider the appropriateness of baby hatches, we present and examine the validity of each major objection to establishing baby hatches. DISCUSSION: There are various objections to baby hatches as follows: It violates a child's right to know the identity of his or her biological parents by allowing anonymous birth; it neglects fulfillment of the biological parents' basic obligation to raise their child and its very availability induces abandonment of infants; some people abuse it for very selfish reasons; it cannot save babies' lives; the rights of one parent can be ignored if the other surrenders a child without his or her consent; it puts a baby in medical jeopardy; and it has no clear legal basis. The authors would argue that there are many plausible refutations for each objection mainly based on priority of child's right to life, pregnant women's vulnerability and necessity of anonymity, social responsibility to protect and raise children, differences between dropping a child off at a baby hatch and child neglect, limited function of social childcare center, inevitability of abuse by a minority of people, necessary distinction between outcomes that occur only because baby hatches exist and those that occur regardless of their existence, important local direct and upmost measures for women in trouble, and difference between ambiguous legality and illegality. SUMMARY: We argue that a certain number of baby hatches should continue to be established as a last resort, in a form that can maintain anonymity if the parent dropping the child off so desires. It should be supported if it is initiated with good intentions; if the maximum possible effort is made at said facility to protect the interests, rights, and safety of the child; and if no clear evidence of harm exists.


Assuntos
Maus-Tratos Infantis , Educação Infantil , Proteção da Criança , Cuidado do Lactente , Pré-Escolar , Feminino , Alemanha , Humanos , Recém-Nascido , Japão , Gravidez
20.
BMC Med Ethics ; 14: 51, 2013 Dec 09.
Artigo em Inglês | MEDLINE | ID: mdl-24321531

RESUMO

BACKGROUND: In Japan, people are negative towards life-prolonging treatments. Laws that regulate withholding or discontinuing life-prolonging treatments and advance directives do not exist. Physicians, however, view discontinuing life-prolonging treatments negatively due to fears of police investigations. Although ministerial guidelines were announced regarding the decision process for end-of-life care in 2007, a consensus could not be reached on the definition of end-of-life and conditions for withholding treatment. We established a forum for extended discussions and consensus building on this topic. METHODS: We used the Neo-Socratic Dialogue (NSD) method which promotes philosophical discussion based on a case-study to address a question and formulate a consensus and answer in a group. The question chosen for the dialogue was: "What is a life-prolonging treatment?" A series of dialogues took place over a period of one and a half days. It was carried out by three groups in 2010 and 2011. Seven participants with diverse backgrounds were recruited per group. We analyzed the content of the discussion. RESULTS: Based on three case studies concerning different opinions about treatment options for an older dementia patient, a patient demanding chemotherapy, and a severely ill neonate, conditions for futile life-prolonging treatment were elucidated through NSD. Such treatments are those carried out for the sole purpose of prolonging life and are detrimental to the patient, and should be decided based foremost on the patient's lack of desire for treatment, the consensus of those involved, and through social acceptance. These arguments are essentially consistent with ones on medical futility in the United States. By expressing the objective of healthcare and the requirement of social acceptance, participants were also able to elucidate issues related to the awareness of those involved and the medical environment. Compared to the end-of-life guidelines in Japan, the objective of treatment, its effects, and benefits were more specifically discussed with the patient's intentions as the foremost consideration, rather than being limited to the terminal stage. CONCLUSIONS: This small study contributed to elucidating the conditions and current problems of futile life-prolonging treatment through NSD. They would suggest more substantial guidelines and improvements on the administration of the treatment.


Assuntos
Diretivas Antecipadas/ética , Tomada de Decisões/ética , Cuidados para Prolongar a Vida/ética , Futilidade Médica/ética , Negociação , Médicos , Ordens quanto à Conduta (Ética Médica)/ética , Suspensão de Tratamento/ética , Idoso de 80 Anos ou mais , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Atitude do Pessoal de Saúde , Comportamento de Escolha/ética , Formação de Conceito , Estado Terminal , Demência , Dissidências e Disputas , Análise Ética , Humanos , Recém-Nascido , Japão , Filosofia Médica , Médicos/ética , Médicos/tendências , Guias de Prática Clínica como Assunto/normas , Opinião Pública , Assistência Terminal/ética
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