Association Between Illness Perception and Care-Seeking Intention in Patients With Chronic Heart Failure.

This study aimed to investigate the association between illness perception and care-seeking intention in Japanese patients with chronic heart failure (CHF). A cross-sectional study was conducted on 160 CHF outpatients with reference to the framework of the Common-Sense Model. Illness perception was measured using the Brief Illness Perception Questionnaire (B-IPQ). Care-seeking intention was assessed based on the intent to consult medical care at the onset of varying symptoms. Association between illness perception and the care-seeking intention was analyzed by logistic regression analysis after univariate analysis. In the univariate analysis, illness perception was only associated with care-seeking intention at the onset of dyspnea at rest. Treatment control, which means the expected effectiveness of treatment in B-IPQ, was associated with care-seeking intention at the onset of dyspnea at rest (OR: 1.261, 95% CI [1.025-1.550]). It may be necessary to assess the patients' perceptions of their treatment and explain its effects.

Evaluation of the effect of a chicken comb extract-containing supplement on cartilage and bone metabolism in athletes.

In a previous study, we revealed that a commercially available product of dietary supplement containing a chicken comb extract (CCE), which is rich in hyaluronan, not only relieves joint pain and other symptoms, but also potentially improves the balance of type II collagen degradation/synthesis in patients with knee osteoarthritis. Since soccer is one of the sports most likely to cause knee osteoarthritis (OA), we evaluated the effect of a CCE-containing supplement on cartilage and bone metabolism in athletes. Fourteen and 15 subjects (all midfielders) were randomly assigned to receive the test product (test group) and the dummy placebo containing only vehicle (placebo group), respectively, for 12 weeks. The daily oral intake of the CCE-containing test product clearly decreased the urinary levels of both C-terminal crosslinked telopeptides of cartilage-specific type II collagen (CTX-II) as a type II collagen degradation marker and the N-terminal telopeptides of bone-specific type I collagen (NTx) as a marker of bone resorption at 12 weeks after the initiation of the intervention. By contrast, no significant reduction was detected in the placebo group at any timepoint during the intervention. These observations indicate that the test product is effective in inhibiting, not only cartilage degradation, but also bone remodeling. Thus, the CCE-containing supplement may be useful for the management of joint health in athletes.