Changes in Hematological Parameters and Liver Enzymes During Laparoscopic Cholecystectomy.

Background Changes in hematological parameters, such as neutrophils, leukocytes, neutrophil-lymphocyte ratio, platelet lymphocyte ratio, and mean platelet volume, have been observed during laparoscopic surgeries. Objectives The objectives of this research were to assess the changes in hematological parameters and liver enzymes during laparoscopic cholecystectomy (LC). Methods This prospective observational study included patients undergoing laparoscopic cholecystectomy for symptomatic cholelithiasis. Patients with comorbidities, including hepatitis, diabetes, and where laparoscopic cholecystectomy was converted to open cholecystectomy, were excluded. Preoperative and postoperative baseline hematological parameters and liver function tests (LFTs) were recorded. Characteristics like age, gender, body mass index (BMI), indication for surgery, duration of surgery, the pressure of pneumoperitoneum, and the duration of hospital stay were noted. A paired sample t-test was applied to assess the difference between the mean pre and postoperative values of different hematological parameters. Results It was observed that hemoglobin (Hb), hematocrit (Hct), platelets, and alkaline phosphatase (ALP) decreased postoperatively. However, mean corpuscular volume (MCV), mean platelet volume (MPV), leukocytes, and alanine transaminase (ALT) increased postoperatively. The difference in mean Hb, MCV, Hct, leukocytes, MPV, and ALT was statistically significant (p<0.05). Conclusion There were significant changes in the levels of hematological parameters and liver enzymes during LC.

Comparison of Mean Fluoroscopic Time and Mean Contrast Volume Used in Patients Undergoing Coronary Angiography by the Transfemoral Versus Transradial Route.

Introduction The prolonged fluoroscopic time during coronary angiography results in a higher radiation dose delivered to patients. Similarly, a higher contrast volume used is associated with higher rates of contrast-induced nephropathy. This study was designed to identify the better technique in terms of lesser fluoroscopic time and volume of contrast used during the procedure. Objective To compare mean fluoroscopic time and mean contrast volume used in patients undergoing coronary angiography through the transfemoral versus transradial route. Methods A randomized controlled trial (RCT) was conducted at the department of cardiology, Pakistan Institute of Medical Sciences (PIMS) Islamabad between June 2017 and December 2017. Ninety (n=90) patients planned for coronary angiography between 30 and 70 years of age were enrolled. Patients were randomly allocated to Group A (transfemoral route group) and Group B (transradial route group). Fluoroscopic time (minutes) and contrast volume (milliliters) used were measured in each patient. Results The mean contrast volume used in Group A was 70.4 ml (SD=8.7) and in Group B, it was 90.1 ml (SD=9.8) (P<0.001). The mean fluoroscopic time in Group A was 5.1 min (SD=1.2), and in group B, it was 8.6 min (SD=1.2) (P<0.001). Similar trends were noted when data were stratified with respect to age and gender. Conclusion The mean fluoroscopic time and the mean contrast volume were significantly less in patients where coronary angiography was performed through the transfemoral route than through the transradial route in this study.

Personality Dynamism and Academic Performance Among Boarders and Non-boarders Studying in a Medical University.

Introduction The personality of a human being consists of his behavior, cognition, emotional abilities, and interaction with his surroundings. The personality of an individual is modified by his ability for social perception, life experiences, and training. The pattern of study in which a person acquires education has a great influence on their personality. Objective To compare the personality traits and academic performance of boarders and non-boarders studying in a medical university. Material and methods It is a comparative, descriptive cross-sectional study done at Rawalpindi Medical University, Pakistan. The duration of the study was from January 2019 to April 2019. A questionnaire was randomly distributed among the students of Rawalpindi Medical University and filled under supervision. The questionnaire had two parts: (1) Academic performance information and (2) Big Five inventory (BFI-40). Only MBBS students of Rawalpindi Medical University were included. For statistical analysis, the independent t-test was applied using the Windows IBM Statistical Package for the Social Sciences Version 22 (SPSS, IBM Corp., Armonk, NY, US). The statistically significant value was taken as 0.05. Results Out of 300 questionnaires distributed, 287 were properly filled, giving a response rate of 95.6%. The Cronbach's alpha value was .750. The mean age was 20.87±1.344. There were 216 (75.1%) male and 71 (24.9%) females. One-hundred eighty-three (63.8%) were boarders and 104 (36.2%) were non-boarders. The mean scores of extraversion, agreeableness, and conscientiousness were higher for boarders while the mean scores of neuroticism and openness were higher for non-boarders. High average percentages in professional exams were common in non-boarders while boarders were taking more supplementary exams comparatively. Conclusion Self-discipline, surgency from external activities/situations, and getting along with others are common traits among boarders. On the other hand, non-boarders are more creative but emotionally unstable. The academic status of boarders is comparatively poor. Thus, the hostel administration should be particularly concerned about the activities of boarders, and parents should be aware of their child's academic status. Teachers should pay special attention to the character development of students.