Detalhe da pesquisa
1.
Functional characterization of a VEGF-A-targeting Anticalin, prototype of a novel therapeutic human protein class.
Angiogenesis
; 19(1): 79-94, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26650228
2.
Towards a consensus definition of immune exclusion in cancer.
Front Immunol
; 14: 1084887, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37033994
3.
Endotrophin, a Key Marker and Driver for Fibroinflammatory Disease.
Endocr Rev
; 2023 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38091968
4.
A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer.
J Immunother Cancer
; 11(6)2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37328286
5.
Neutrophil-derived leukotriene B4 is required for inflammatory arthritis.
J Exp Med
; 203(4): 837-42, 2006 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16567388
6.
A novel role of prostaglandin E2 in neuropathic pain: blockade of microglial migration in the spinal cord.
Glia
; 59(2): 208-18, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21125641
7.
Microsomal prostaglandin E2 synthase-1 deletion leads to adverse left ventricular remodeling after myocardial infarction.
Circulation
; 117(13): 1701-10, 2008 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18347209
8.
Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis.
Prostaglandins Other Lipid Mediat
; 88(3-4): 73-81, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19010439
9.
MF63 [2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation.
J Pharmacol Exp Ther
; 326(3): 754-63, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18524979
10.
MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis.
J Pharmacol Exp Ther
; 325(2): 425-34, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18287210
11.
Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis.
Nat Neurosci
; 6(11): 1137-8, 2003 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-14566340
12.
A novel psychoanalytical approach: An electrochemical ligand-binding assay to screen antipsychotics.
Biosens Bioelectron
; 100: 139-147, 2018 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28886458
13.
Sustained plasma hepcidin suppression and iron elevation by Anticalin-derived hepcidin antagonist in cynomolgus monkey.
Br J Pharmacol
; 175(7): 1054-1065, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29329501
14.
The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis.
J Clin Invest
; 110(5): 651-8, 2002 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12208866
15.
Pharmacological characterization of a selective COX-2 inhibitor MF-tricyclic, [3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone], in multiple preclinical species.
Eur J Pharmacol
; 560(2-3): 216-24, 2007 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-17316604
16.
Actinic keratosis modelling in mice: A translational study.
PLoS One
; 12(6): e0179991, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28662116
17.
Metabolism of PGE2 by prostaglandin dehydrogenase is essential for remodeling the ductus arteriosus.
Nat Med
; 8(2): 91-2, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11821873
18.
Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption.
Mol Endocrinol
; 17(7): 1356-67, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12677010
19.
Inhibition of IL-1beta-dependent prostaglandin E2 release by antisense microsomal prostaglandin E synthase 1 oligonucleotides in A549 cells.
Mol Cell Endocrinol
; 205(1-2): 151-7, 2003 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-12890577
20.
In vivo visualization of MET tumor expression and anticalin biodistribution with the MET-specific anticalin 89Zr-PRS-110 PET tracer.
J Nucl Med
; 55(4): 665-71, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24614223