RESUMO
After a period of heavy rainfall, an outbreak of Rift Valley fever occurred in southern Mauritania during September-November 2012. A total of 41 human cases were confirmed, including 13 deaths, and 12 Rift Valley fever virus strains were isolated. Moudjeria and Temchecket Departments were the most affected areas.
Assuntos
Culicidae/virologia , Surtos de Doenças , Insetos Vetores/virologia , Febre do Vale de Rift/epidemiologia , Vírus da Febre do Vale do Rift/genética , Proteínas Virais/genética , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Animais , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Mauritânia/epidemiologia , Pessoa de Meia-Idade , Filogenia , Febre do Vale de Rift/mortalidade , Febre do Vale de Rift/transmissão , Febre do Vale de Rift/virologia , Vírus da Febre do Vale do Rift/classificação , Estações do Ano , Análise de Sobrevida , Proteínas Virais/classificaçãoRESUMO
A Rift Valley fever (RVF) outbreak in humans and animals occurred in Mauritania in 2010. Thirty cases of RVF in humans and 3 deaths were identified. RVFV isolates were recovered from humans, camels, sheep, goats, and Culex antennatus mosquitoes. Phylogenetic analysis of isolates indicated a virus origin from western Africa.
Assuntos
Culex/virologia , Surtos de Doenças , Insetos Vetores/virologia , RNA Viral/genética , Febre do Vale de Rift/epidemiologia , Vírus da Febre do Vale do Rift/genética , Adolescente , Adulto , Idoso , Animais , Camelus/virologia , Feminino , Cabras/virologia , Humanos , Masculino , Mauritânia/epidemiologia , Pessoa de Meia-Idade , Filogenia , RNA Viral/classificação , Estudos Retrospectivos , Febre do Vale de Rift/mortalidade , Febre do Vale de Rift/transmissão , Febre do Vale de Rift/virologia , Vírus da Febre do Vale do Rift/classificação , Ovinos/virologia , Análise de SobrevidaRESUMO
In October 2003, 9 human cases of hemorrhagic fever were reported in 3 provinces of Mauritania, West Africa. Test results showed acute Rift Valley fever virus (RVFV) infection, and a field investigation found recent circulation of RVFV with a prevalence rate of 25.5% (25/98) and 4 deaths among the 25 laboratory-confirmed case-patients. Immunoglobulin M against RVFV was found in 46% (25/54) of domestic animals. RVFV was also isolated from the mosquito species Culex poicilipes. Genetic comparison of virion segments indicated little variation among the strains isolated. However, phylogenetic studies clearly demonstrated that these strains belonged to the East-Central African lineage for all segments. To our knowledge, this is the first time viruses of this lineage have been observed in an outbreak in West Africa. Whether these strains were introduced or are endemic in West Africa remains to be determined.