Detalhe da pesquisa
1.
Clinical Ocular Exposure Extrapolation for Ophthalmic Solutions Using PBPK Modeling and Simulation.
Pharm Res
; 40(2): 431-447, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36151444
2.
Computational Model of In Vivo Corneal Pharmacokinetics and Pharmacodynamics of Topically Administered Ophthalmic Drug Products.
Pharm Res
; 40(4): 961-975, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36959411
3.
Research and Education Needs for Complex Generics.
Pharm Res
; 38(12): 1991-2001, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34950975
4.
Ocular Physiologically Based Pharmacokinetic Modeling for Ointment Formulations.
Pharm Res
; 37(12): 245, 2020 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33215336
5.
Transport and deposition of hygroscopic particles in asthmatic subjects with and without airway narrowing.
J Aerosol Sci
; 146: 105581, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32346183
6.
Identification of non-reported bupropion metabolites in human plasma.
Biopharm Drug Dispos
; 37(9): 550-560, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27723114
7.
Metabolism of bupropion by carbonyl reductases in liver and intestine.
Drug Metab Dispos
; 43(7): 1019-27, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25904761
8.
Use of physiologically-based pharmacokinetic modeling to understand the effect of omeprazole administration on the pharmacokinetics of oral extended-release nifedipine.
CPT Pharmacometrics Syst Pharmacol
; 13(2): 247-256, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38130031
9.
Use of the Same Model or Modeling Strategy Across Multiple Submissions: Focus on Complex Drug Products.
AAPS J
; 26(1): 12, 2024 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38177638
10.
Synthetic RNA modules for fine-tuning gene expression levels in yeast by modulating RNase III activity.
Nucleic Acids Res
; 39(19): 8651-64, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21737428
11.
Engineering ligand-responsive RNA controllers in yeast through the assembly of RNase III tuning modules.
Nucleic Acids Res
; 39(12): 5299-311, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21355039
12.
Transport and deposition of beclomethasone dipropionate drug aerosols with varying ethanol concentration in severe asthmatic subjects.
Int J Pharm
; 636: 122805, 2023 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36898619
13.
Establishing quantitative relationships between changes in nasal spray in vitro metrics and drug delivery to the posterior nasal region.
Int J Pharm
; 635: 122718, 2023 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36781083
14.
Mechanistic modeling of ophthalmic, nasal, injectable, and implant generic drug products: A workshop summary report.
CPT Pharmacometrics Syst Pharmacol
; 12(5): 631-638, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36851886
15.
Regulatory utility of mechanistic modeling to support alternative bioequivalence approaches: A workshop overview.
CPT Pharmacometrics Syst Pharmacol
; 12(5): 619-623, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36631942
16.
Topical pharmacokinetics of brinzolamide suspensions in rabbits and variability analysis for sample size and design considerations.
Int J Pharm
; 642: 123183, 2023 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37369289
17.
A synthetic library of RNA control modules for predictable tuning of gene expression in yeast.
Mol Syst Biol
; 7: 471, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21364573
18.
Physiologically-Based Pharmacokinetic Modeling to Support Determination of Bioequivalence for Dermatological Drug Products: Scientific and Regulatory Considerations.
Clin Pharmacol Ther
; 111(5): 1036-1049, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34231211
19.
Anatomically realistic nasal replicas capturing the range of nasal spray drug delivery in adults.
Int J Pharm
; 622: 121858, 2022 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35643344
20.
Considerations for the Forced Expiratory Volume in 1 Second-Based Comparative Clinical Endpoint Bioequivalence Studies for Orally Inhaled Drug Products.
Clin Pharmacol Ther
; 112(5): 982-989, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35133652