Detalhe da pesquisa
1.
Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aß Pool.
Cell
; 166(1): 193-208, 2016 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27293189
2.
ARF6-mediated endosomal transport of Telencephalin affects dendritic filopodia-to-spine maturation.
EMBO J
; 31(15): 3252-69, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22781129
3.
Peptides based on the presenilin-APP binding domain inhibit APP processing and Aß production through interfering with the APP transmembrane domain.
FASEB J
; 26(9): 3765-78, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22661005
4.
Rer1p competes with APH-1 for binding to nicastrin and regulates gamma-secretase complex assembly in the early secretory pathway.
J Cell Biol
; 176(5): 629-40, 2007 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-17325205
5.
Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway.
J Cell Biol
; 166(7): 1041-54, 2004 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-15452145
6.
An Administrator's Perspective on the Organization of Physical Activity for Older Adults in Long-Term Care Facilities.
J Am Med Dir Assoc
; 17(1): 75-84, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26432625
7.
Motivators and barriers for physical activity in older adults with osteoporosis.
J Geriatr Phys Ther
; 38(3): 105-14, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25594524
8.
Physiotherapists' perceived motivators and barriers for organizing physical activity for older long-term care facility residents.
J Am Med Dir Assoc
; 16(5): 371-9, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25669669
9.
Rer1p maintains ciliary length and signaling by regulating γ-secretase activity and Foxj1a levels.
J Cell Biol
; 200(6): 709-20, 2013 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23479743
10.
Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells.
J Cell Biol
; 198(1): 23-35, 2012 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22753898
11.
Motivators and barriers for physical activity in the oldest old: a systematic review.
Ageing Res Rev
; 10(4): 464-74, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21570493
12.
Presenilin-1 maintains a nine-transmembrane topology throughout the secretory pathway.
J Biol Chem
; 281(36): 26569-77, 2006 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-16846981
13.
Coordinated and widespread expression of gamma-secretase in vivo: evidence for size and molecular heterogeneity.
Neurobiol Dis
; 17(2): 260-72, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15474363