Detalhe da pesquisa
1.
De novo protein design by deep network hallucination.
Nature
; 600(7889): 547-552, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34853475
2.
Insights into Structural and Dynamical Changes Experienced by Human RNase 6 upon Ligand Binding.
Biochemistry
; 59(6): 755-765, 2020 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31909602
3.
Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics.
Biochemistry
; 57(40): 5864-5876, 2018 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30204415
4.
Small Angle Neutron Scattering Studies of R67 Dihydrofolate Reductase, a Tetrameric Protein with Intrinsically Disordered N-Termini.
Biochemistry
; 56(44): 5886-5899, 2017 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29020453
5.
Applications of NMR and computational methodologies to study protein dynamics.
Arch Biochem Biophys
; 628: 71-80, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28483383
6.
Aspects of Weak Interactions between Folate and Glycine Betaine.
Biochemistry
; 55(45): 6282-6294, 2016 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27768285
7.
Protocol for production and purification of SARS-CoV-2 3CLpro.
STAR Protoc
; 4(2): 102326, 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37235475
8.
Conformational exchange divergence along the evolutionary pathway of eosinophil-associated ribonucleases.
Structure
; 31(3): 329-342.e4, 2023 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36649708
9.
Structural similarities between SARS-CoV2 3CLpro and other viral proteases suggest potential lead molecules for developing broad spectrum antivirals.
Front Chem
; 10: 948553, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36353143
10.
Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture.
Cell Rep
; 35(7): 109133, 2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33984267
11.
Structural Similarity of SARS-CoV2 Mpro and HCV NS3/4A Proteases Suggests New Approaches for Identifying Existing Drugs Useful as COVID-19 Therapeutics.
ChemRxiv
; 2020 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511291
12.
Enzyme dynamics: Looking beyond a single structure.
ChemCatChem
; 12(19): 4704-4720, 2020 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33897908
13.
Nucleotide substrate binding characterization in human pancreatic-type ribonucleases.
PLoS One
; 14(8): e0220037, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31393891
14.
Ligand-Induced Variations in Structural and Dynamical Properties Within an Enzyme Superfamily.
Front Mol Biosci
; 5: 54, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29946547
15.
Conservation of Dynamics Associated with Biological Function in an Enzyme Superfamily.
Structure
; 26(3): 426-436.e3, 2018 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29478822
16.
Correction to: Sequence-specific backbone resonance assignments and microsecond timescale molecular dynamics simulation of human eosinophil-derived neurotoxin.
Biomol NMR Assign
; 12(2): 365-367, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30083869
17.
Sequence-specific backbone resonance assignments and microsecond timescale molecular dynamics simulation of human eosinophil-derived neurotoxin.
Biomol NMR Assign
; 11(2): 143-149, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28271277
18.
Computational Structure-Based De Novo Design of Hypothetical Inhibitors against the Anti- Inflammatory Target COX-2.
PLoS One
; 10(8): e0134691, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26241744
19.
The bitter barricading of prostaglandin biosynthesis pathway: understanding the molecular mechanism of selective cyclooxygenase-2 inhibition by amarogentin, a secoiridoid glycoside from Swertia chirayita.
PLoS One
; 9(6): e90637, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24603686