Detalhe da pesquisa
1.
A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer.
J Pharmacol Exp Ther
; 353(2): 392-404, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25720766
2.
Identification of novel drugs to target dormant micrometastases.
BMC Cancer
; 15: 404, 2015 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25971923
3.
The design and discovery of water soluble 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multitargeted receptor tyrosine kinase inhibitors and microtubule targeting antitumor agents.
Bioorg Med Chem
; 22(14): 3753-72, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24890652
4.
Selenium Deficiency Exacerbates Hyperoxia-Induced Lung Injury in Newborn C3H/HeN Mice.
Antioxidants (Basel)
; 13(4)2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38671839
5.
Solid phase synthesis and biological evaluation of probestin as an angiogenesis inhibitor.
Bioorg Med Chem Lett
; 23(12): 3561-4, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23664876
6.
N2-Trimethylacetyl substituted and unsubstituted-N4-phenylsubstituted-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines: design, cellular receptor tyrosine kinase inhibitory activities and in vivo evaluation as antiangiogenic, antimetastatic and antitumor agents.
Bioorg Med Chem
; 21(5): 1312-23, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23375090
7.
Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents.
Bioorg Med Chem
; 20(14): 4217-25, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22739090
8.
17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior.
Aging Cell
; 17(1)2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29168299
9.
Discovery of antitubulin agents with antiangiogenic activity as single entities with multitarget chemotherapy potential.
ACS Med Chem Lett
; 5(5): 480-4, 2014 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900865
10.
Development and characterization of a preclinical model of breast cancer lung micrometastatic to macrometastatic progression.
PLoS One
; 9(5): e98624, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24878664
11.
Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation.
J Gerontol A Biol Sci Med Sci
; 68(7): 780-92, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23213032
12.
Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging.
J Gerontol A Biol Sci Med Sci
; 67(6): 553-64, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22080499
13.
Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging.
J Gerontol A Biol Sci Med Sci
; 67(4): 313-29, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22021391