Detalhe da pesquisa
1.
Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation.
Blood
; 139(7): 1066-1079, 2022 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34699595
2.
Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML.
Blood
; 130(4): 397-407, 2017 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28576879
3.
Clonal haemopoiesis and therapy-related myeloid malignancies in elderly patients: a proof-of-concept, case-control study.
Lancet Oncol
; 18(1): 112-121, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27927582
4.
Phase 1 study of lenzilumab, a recombinant anti-human GM-CSF antibody, for chronic myelomonocytic leukemia.
Blood
; 136(7): 909-913, 2020 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32294158
5.
Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim.
Mar Drugs
; 12(8): 4311-25, 2014 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25076060
6.
Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim.
Mar Drugs
; 12(3): 1335-48, 2014 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24608970
7.
Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML.
Clin Cancer Res
; 29(15): 2919-2932, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37223910
8.
Synthesis and evaluation of substituted hexahydronaphthalenes as novel inhibitors of the Mcl-1/BimBH3 interaction.
Bioorg Med Chem Lett
; 22(18): 5961-5, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22901384
9.
Progenitor Hierarchy of Chronic Myelomonocytic Leukemia Identifies Inflammatory Monocytic-Biased Trajectory Linked to Worse Outcomes.
Blood Cancer Discov
; 3(6): 536-553, 2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36053528
10.
Integrated Human and Murine Clinical Study Establishes Clinical Efficacy of Ruxolitinib in Chronic Myelomonocytic Leukemia.
Clin Cancer Res
; 27(22): 6095-6105, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34253584
11.
RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis.
Nat Commun
; 12(1): 2901, 2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34006870
12.
Effects of Corynebacterium bovis on Engraftment of Patient-derived Chronic-Myelomonocytic Leukemia Cells in NSGS Mice.
Comp Med
; 69(4): 276-282, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31349880
13.
Heterogeneous expression of cytokines accounts for clinical diversity and refines prognostication in CMML.
Leukemia
; 33(1): 205-216, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30026572
14.
Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays.
Clin Cancer Res
; 24(23): 5918-5924, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29866652
15.
Cotreatment with vorinostat (suberoylanilide hydroxamic acid) enhances activity of dasatinib (BMS-354825) against imatinib mesylate-sensitive or imatinib mesylate-resistant chronic myelogenous leukemia cells.
Clin Cancer Res
; 12(19): 5869-78, 2006 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17020995
16.
Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin.
Cancer Res
; 65(22): 10536-44, 2005 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16288046
17.
Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells.
Mol Cancer Ther
; 5(12): 3096-104, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17172412
18.
Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2.
Clin Cancer Res
; 11(17): 6382-9, 2005 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16144943
19.
A Multi-Institution Phase I Trial of Ruxolitinib in Patients with Chronic Myelomonocytic Leukemia (CMML).
Clin Cancer Res
; 22(15): 3746-54, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26858309
20.
Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors.
Eur J Med Chem
; 90: 315-331, 2015 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25437618