Detalhe da pesquisa
1.
Golexanolone improves fatigue, motor incoordination and gait and memory in rats with bile duct ligation.
Liver Int
; 44(2): 433-445, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38010893
2.
Active Clinical Trials in Hepatic Encephalopathy: Something Old, Something New and Something Borrowed.
Neurochem Res
; 48(8): 2309-2319, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-36977964
3.
Patients who died with steatohepatitis or liver cirrhosis show neuroinflammation and neuronal loss in hippocampus.
Eur J Neurol
; 30(10): 3032-3046, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37340928
4.
The S1PR2-CCL2-BDNF-TrkB pathway mediates neuroinflammation and motor incoordination in hyperammonaemia.
Neuropathol Appl Neurobiol
; 48(4): e12799, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35152448
5.
The Dual Role of the GABAA Receptor in Peripheral Inflammation and Neuroinflammation: A Study in Hyperammonemic Rats.
Int J Mol Sci
; 22(13)2021 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34202516
6.
Chronic hyperammonemia induces peripheral inflammation that leads to cognitive impairment in rats: Reversed by anti-TNF-α treatment.
J Hepatol
; 73(3): 582-592, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30654069
7.
Sustained hyperammonemia induces TNF-a IN Purkinje neurons by activating the TNFR1-NF-κB pathway.
J Neuroinflammation
; 17(1): 70, 2020 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32087723
8.
Differential role of interleukin-1ß in neuroinflammation-induced impairment of spatial and nonspatial memory in hyperammonemic rats.
FASEB J
; 33(9): 9913-9928, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31162953
9.
Increasing extracellular cGMP in cerebellum in vivo reduces neuroinflammation, GABAergic tone and motor in-coordination in hyperammonemic rats.
Brain Behav Immun
; 69: 386-398, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29288802
10.
Neuroinflammation increases GABAergic tone and impairs cognitive and motor function in hyperammonemia by increasing GAT-3 membrane expression. Reversal by sulforaphane by promoting M2 polarization of microglia.
J Neuroinflammation
; 13(1): 83, 2016 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27090509
11.
Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy.
J Neuroinflammation
; 13(1): 245, 2016 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27623772
12.
In vivo administration of extracellular cGMP normalizes TNF-α and membrane expression of AMPA receptors in hippocampus and spatial reference memory but not IL-1ß, NMDA receptors in membrane and working memory in hyperammonemic rats.
Brain Behav Immun
; 57: 360-370, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27189036
13.
Neuroinflammation, immune response and α-synuclein pathology: how animal models are helping us to connect dots.
Expert Opin Drug Discov
; 18(1): 13-23, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36538833
14.
Hepatic encephalopathy: investigational drugs in preclinical and early phase development.
Expert Opin Investig Drugs
; 32(11): 1055-1069, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37902074
15.
BBB opening with focused ultrasound in nonhuman primates and Parkinson's disease patients: Targeted AAV vector delivery and PET imaging.
Sci Adv
; 9(16): eadf4888, 2023 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37075119
16.
Rifaximin Improves Spatial Learning and Memory Impairment in Rats with Liver Damage-Associated Neuroinflammation.
Biomedicines
; 10(6)2022 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35740285
17.
Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage.
Biomedicines
; 9(8)2021 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34440206
18.
Lack of Parkinsonian Pathology and Neurodegeneration in Mice After Long-Term Injections of a Proteasome Inhibitor in Olfactory Bulb and Amygdala.
Front Aging Neurosci
; 13: 698979, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34744683
19.
Bacteroides uniformis CECT 7771 Modulates the Brain Reward Response to Reduce Binge Eating and Anxiety-Like Behavior in Rat.
Mol Neurobiol
; 58(10): 4959-4979, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34228269
20.
Bicuculline Reduces Neuroinflammation in Hippocampus and Improves Spatial Learning and Anxiety in Hyperammonemic Rats. Role of Glutamate Receptors.
Front Pharmacol
; 10: 132, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30858801