Detalhe da pesquisa
1.
Evinacumab for Pediatric Patients With Homozygous Familial Hypercholesterolemia.
Circulation
; 149(5): 343-353, 2024 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37860863
2.
Evinacumab Reduces Triglyceride-Rich Lipoproteins in Patients with Hyperlipidemia: A Post-Hoc Analysis of Three Randomized Clinical Trials.
Cardiovasc Drugs Ther
; 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38446275
3.
Evinacumab for Homozygous Familial Hypercholesterolemia.
N Engl J Med
; 383(8): 711-720, 2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32813947
4.
Patients With High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit From Alirocumab Treatment in the ODYSSEY OUTCOMES Trial.
Circulation
; 141(8): 624-636, 2020 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31707832
5.
Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance.
J Lipid Res
; 61(9): 1271-1286, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32646941
6.
Inhibition of Angiopoietin-Like Protein 3 With a Monoclonal Antibody Reduces Triglycerides in Hypertriglyceridemia.
Circulation
; 140(6): 470-486, 2019 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31242752
7.
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.
N Engl J Med
; 377(3): 211-221, 2017 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28538136
8.
Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants in Patient Lymphocytes to Assess the Effect of Evinacumab in Homozygous Familial Hypercholesterolemia Patients With a Spectrum of LDLR Activity.
Arterioscler Thromb Vasc Biol
; 39(11): 2248-2260, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578082
9.
Effect of alirocumab on specific lipoprotein non-high-density lipoprotein cholesterol and subfractions as measured by the vertical auto profile method: analysis of 3 randomized trials versus placebo.
Lipids Health Dis
; 15: 28, 2016 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26872608
10.
ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia.
N Engl J Med
; 377(3): 296-297, 2017 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28723334
11.
Plasma levels of amyloid beta and other proinflammatory mediators in patients with age-related macular degeneration.
Graefes Arch Clin Exp Ophthalmol
; 253(8): 1347-54, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25744331
12.
Evinacumab in severe hypertriglyceridemia with or without lipoprotein lipase pathway mutations: a phase 2 randomized trial.
Nat Med
; 29(3): 729-737, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36879129
13.
Pharmacogenomic Study of Statin-Associated Muscle Symptoms in the ODYSSEY OUTCOMES Trial.
Circ Genom Precis Med
; 15(3): e003503, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35543701
14.
Efficacy and Safety of Alirocumab in Adults With Homozygous Familial Hypercholesterolemia: The ODYSSEY HoFH Trial.
J Am Coll Cardiol
; 76(2): 131-142, 2020 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32646561
15.
Genetic Polymorphisms Associated with Idiopathic Short Stature and First-Year Response to Growth Hormone Treatment.
Horm Res Paediatr
; 91(3): 164-174, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30970347
16.
Alirocumab efficacy in patients with double heterozygous, compound heterozygous, or homozygous familial hypercholesterolemia.
J Clin Lipidol
; 12(2): 390-396.e8, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29396260
17.
Efficacy of alirocumab in 1191 patients with a wide spectrum of mutations in genes causative for familial hypercholesterolemia.
J Clin Lipidol
; 11(6): 1338-1346.e7, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28964736
18.
A Quantitative Systems Pharmacology Platform to Investigate the Impact of Alirocumab and Cholesterol-Lowering Therapies on Lipid Profiles and Plaque Characteristics.
Gene Regul Syst Bio
; 11: 1177625017710941, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28804243
19.
Inhibition of Angiopoietin-Like Protein 3 With Evinacumab in Subjects With High and Severe Hypertriglyceridemia.
J Am Coll Cardiol
; 78(2): 193-195, 2021 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34238441
20.
Corrigendum to "Efficacy of alirocumab in 1191 patients with a wide spectrum of mutations in genes causative for familial hypercholesterolemia" J Clin Lipidol 11 (2017) 1338-1346.
J Clin Lipidol
; 14(5): 742, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33138962