Detalhe da pesquisa
1.
Prevalence and characterization of piperaquine, mefloquine and artemisinin derivatives triple-resistant Plasmodium falciparum in Cambodia.
J Antimicrob Chemother
; 78(2): 411-417, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36508338
2.
A molecular marker of artemisinin-resistant Plasmodium falciparum malaria.
Nature
; 505(7481): 50-5, 2014 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24352242
3.
In vitro activity of ferroquine against artemisinin-based combination therapy (ACT)-resistant Plasmodium falciparum isolates from Cambodia.
J Antimicrob Chemother
; 74(11): 3240-3244, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31518407
4.
A key role for Plasmodium subtilisin-like SUB1 protease in egress of malaria parasites from host hepatocytes.
J Biol Chem
; 288(46): 33336-46, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24089525
5.
In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound.
J Biol Chem
; 288(25): 18561-73, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23653352
6.
Cytometric measurement of in vitro inhibition of Plasmodium falciparum field isolates by drugs: a new approach for re-invasion inhibition study.
Malar J
; 13: 110, 2014 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24649924
7.
Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls Plasmodium Sub1 activity before merozoite egress.
mBio
; 15(3): e0019824, 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38386597
8.
Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1.
Eur J Med Chem
; 269: 116308, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38503166
9.
Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia.
Antimicrob Agents Chemother
; 57(2): 914-23, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23208708
10.
3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived α-ketoamide inhibitor.
Acta Crystallogr D Struct Biol
; 79(Pt 8): 721-734, 2023 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37428845
11.
Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target.
Cell Rep
; 39(11): 110923, 2022 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35705035
12.
Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites.
Life Sci Alliance
; 5(3)2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34857648
13.
A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study.
Lancet Infect Dis
; 17(2): 174-183, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27818097
14.
CyProQuant-PCR: a real time RT-PCR technique for profiling human cytokines, based on external RNA standards, readily automatable for clinical use.
BMC Immunol
; 6: 5, 2005 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15748278
15.
LANCL1, an erythrocyte protein recruited to the Maurer's clefts during Plasmodium falciparum development.
Mol Biochem Parasitol
; 141(1): 39-47, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15811525
16.
A small-molecule cell-based screen led to the identification of biphenylimidazoazines with highly potent and broad-spectrum anti-apicomplexan activity.
Eur J Med Chem
; 89: 386-400, 2015 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25462254
17.
Three multigene families in Plasmodium parasites: facts and questions.
Int J Parasitol
; 32(11): 1323-44, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12350369
18.
Computational design of protein-based inhibitors of Plasmodium vivax subtilisin-like 1 protease.
PLoS One
; 9(10): e109269, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25343504
19.
Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens.
PLoS One
; 9(1): e86658, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24475165
20.
A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase.
Nat Commun
; 5: 4833, 2014 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25204226