Detalhe da pesquisa
1.
Trinucleotide mRNA Cap Analogue N6-Benzylated at the Site of Posttranscriptional m6Am Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo.
J Am Chem Soc
; 146(12): 8149-8163, 2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38442005
2.
Synthesis, kinetic studies, and QSAR of dinucleoside polyphosphate derivatives as human AK1 inhibitors.
Bioorg Chem
; 148: 107432, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38744169
3.
5'-fluoro(di)phosphate-labeled oligonucleotides are versatile molecular probes for studying nucleic acid secondary structure and interactions by 19F NMR.
Nucleic Acids Res
; 48(15): 8209-8224, 2020 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32514551
4.
Synthesis of Trifluoromethylated Purine Ribonucleotides and Their Evaluation as 19F NMR Probes.
J Org Chem
; 85(5): 3440-3453, 2020 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31994393
5.
mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.
Nucleic Acids Res
; 45(15): 8661-8675, 2017 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28666355
6.
7-Methylguanosine monophosphate analogues with 5'-(1,2,3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase.
Bioorg Med Chem
; 26(1): 191-199, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29195795
7.
Synthesis of fluorophosphate nucleotide analogues and their characterization as tools for ¹9F NMR studies.
J Org Chem
; 80(8): 3982-97, 2015 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25816092
8.
Fluorinated Phosphoadenosine 5'-Phosphosulfate Analogues for Continuous Sulfotransferase Activity Monitoring and Inhibitor Screening by 19F NMR Spectroscopy.
ACS Chem Biol
; 17(3): 661-669, 2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35196009
9.
Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism.
Pharmaceuticals (Basel)
; 15(5)2022 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35631380
10.
Protein Tyrosine Phosphatase Biochemical Inhibition Assays.
Bio Protoc
; 12(18)2022 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36248604
11.
Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase.
Viruses
; 13(9)2021 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34578302
12.
Novel N7-Arylmethyl Substituted Dinucleotide mRNA 5' cap Analogs: Synthesis and Evaluation as Modulators of Translation.
Pharmaceutics
; 13(11)2021 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34834356
13.
Purine and pyrimidine dinucleoside polyphosphates differentially affect the phenylpropanoid pathway in Vitis vinifera L. cv. Monastrell suspension cultured cells.
Plant Physiol Biochem
; 147: 125-132, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31855818