Application of Radiomics in Vesselness Analysis of CT Angiography Images of Stroke Patients.

Development of vascular collaterals in a lesion area is one of the key factors that determine not only the choice of treatment for ischemic stroke (IS) patients, but also outcome and therapy effectiveness. The main method for examining the vessels' ramification is CT angiography (CTA). CTA analysis may be improved by incorporating filters designed to extract more features about vessels and quantify their level of development. This work suggests the usage of radiomics methods in the analysis of vesselness measure calculated from CTA images. Vesselness measurement is based on the analysis of the Hessian matrix with a few modifications dictated by practical aspects of this issue. The developed algorithm was implemented as a filter that generates a new 3D image, every voxel of which has the probability of belonging to a vessel-like structure. Further analysis of the distribution of vesselness in the lesion area and in the intact contralateral area was conducted with the methods from the open library PyRadiomics. A set of radiomics features was calculated. Preliminary analysis on a sample of 30 IS patients showed the presence of significant differences between afflicted and intact hemispheres.

Synbiotic yoghurt with walnut and cereal brittle added as a next-generation bioactive compound: Development and characteristics.

The article presents a technology developed for the production of synbiotic Yoghurt with new bioactive filler based on natural components. The Yoghurt has prebiotic and sorption properties. A higher consumer appeal of the product developed has been substantiated; its characteristics compared with the Yoghurt of traditional production technology have been presented. The brittle, containing peeled walnuts, as well as barley, wheat, rye, oatmeal and buckwheat flakes, sugar, and water, was used as a filler. Optimum time and temperature regimes of boiling caramel mixtures and brewing raw walnut-cereal mass in the brittle have been selected. The formulation developed enables increasing the nutritional and biological values of the finished product. The research studies of the finished product involved an analysis of organoleptic, physicochemical, and microbiological points. When performing the tasks, the approved regulatory and technical documentation (GOST) was applied. Each measurement was carried out in triplicate. The physicochemical characteristics of the samples developed were compared with the requirements for the quality of fermented milk products. The nutritional and biological values were calculated. The increase in consumer properties, and nutritional and biological values of the finished dairy product was scientifically substantiated and experimentally confirmed.