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J Pediatr Hematol Oncol ; 43(1): e123-e126, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-32459718

RESUMO

BACKGROUND: Prior reports have shown the utility of conventional lipiodol-based transarterial chemoembolization in hepatoblastoma. The authors describe the first reported case of hepatoblastoma treated with drug-eluting bead transarterial chemoembolization (DEB-TACE). OBSERVATIONS: An 11-month-old infant presented with hepatoblastoma measuring 14.3 cm. A trial of cisplatin chemotherapy followed by sequential DEB-TACE to the tumor's feeding vasculature reduced the mass to 5.3 cm. The patient tolerated both sessions of DEB-TACE without any major complication. Having demonstrated adequate disease control, the patient then underwent successful liver transplantation. CONCLUSION: This report provides promising evidence for the treatment of hepatoblastoma with DEB-TACE.


Assuntos
Antineoplásicos/uso terapêutico , Quimioembolização Terapêutica/métodos , Cisplatino/uso terapêutico , Hepatoblastoma/terapia , Neoplasias Hepáticas/terapia , Transplante de Fígado/métodos , Terapia Combinada , Feminino , Hepatoblastoma/patologia , Humanos , Lactente , Neoplasias Hepáticas/patologia , Prognóstico
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