Detalhe da pesquisa
1.
Iron-export ferroxidase activity of ß-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.
Cell
; 142(6): 857-67, 2010 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20817278
2.
Loss-of-function and gain-of-function studies refute the hypothesis that tau protein is causally involved in the pathogenesis of Huntington's disease.
Hum Mol Genet
; 31(12): 1997-2009, 2022 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34999772
3.
Exploring the significance of lipids in Alzheimer's disease and the potential of extracellular vesicles.
Proteomics
; : e2300063, 2023 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37654087
4.
Isolated rapid eye movement sleep behaviour disorder (iRBD) in the Island Study Linking Ageing and Neurodegenerative Disease (ISLAND) Sleep Study: protocol and baseline characteristics.
J Sleep Res
; : e14109, 2023 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38014898
5.
Modification of Biodistribution and Brain Uptake of Copper Bis(thiosemicarbazonato) Complexes by the Incorporation of Amine and Polyamine Functional Groups.
Inorg Chem
; 58(7): 4540-4552, 2019 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30869878
6.
Amyloid-ß Peptide Aß3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization, and Calcium Influx in Neurons.
J Biol Chem
; 291(12): 6134-45, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26697885
7.
Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry.
Anal Chem
; 89(11): 6136-6145, 2017 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28453255
8.
Stabilization of nontoxic Aß-oligomers: insights into the mechanism of action of hydroxyquinolines in Alzheimer's disease.
J Neurosci
; 35(7): 2871-84, 2015 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25698727
9.
Synthesis of Oxorhenium(V) and Oxotechnetium(V) Complexes That Bind to Amyloid-ß Plaques.
Inorg Chem
; 55(16): 7944-53, 2016 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27459001
10.
Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis.
J Neurosci
; 34(23): 8021-31, 2014 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24899723
11.
PBT2 inhibits glutamate-induced excitotoxicity in neurons through metal-mediated preconditioning.
Neurobiol Dis
; 81: 176-85, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25697105
12.
Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality.
J Virol
; 88(5): 2690-703, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24352465
13.
Synthesis of 2-pyridyl-benzimidazole iridium(III), ruthenium(II), and platinum(II) complexes. study of the activity as inhibitors of amyloid-ß aggregation and neurotoxicity evaluation.
Inorg Chem
; 54(2): 470-5, 2015 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25409492
14.
C-terminal peptides modelling constitutive PrPC processing demonstrate ameliorated toxicity predisposition consequent to α-cleavage.
Biochem J
; 459(1): 103-15, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24438129
15.
Biological metals and metal-targeting compounds in major neurodegenerative diseases.
Chem Soc Rev
; 43(19): 6727-49, 2014 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25099276
16.
A Functional Role for Aß in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding.
Angew Chem Int Ed Engl
; 54(36): 10460-4, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26178596
17.
Guanidine hydrochloride denaturation of dopamine-induced α-synuclein oligomers: a small-angle X-ray scattering study.
Proteins
; 82(1): 10-21, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23733394
18.
Do current therapeutic anti-Aß antibodies for Alzheimer's disease engage the target?
Acta Neuropathol
; 127(6): 803-10, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24803227
19.
Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease.
Alzheimers Dement
; 10(1): 53-61, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23491263
20.
Do Bacterial Outer Membrane Vesicles Contribute to Chronic Inflammation in Parkinson's Disease?
J Parkinsons Dis
; 14(2): 227-244, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38427502