Detalhe da pesquisa
1.
PAK3 activation promotes the tangential to radial migration switch of cortical interneurons by increasing leading process dynamics and disrupting cell polarity.
Mol Psychiatry
; 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38454080
2.
Antagonistic actions of PAK1 and NF2/Merlin drive myelin membrane expansion in oligodendrocytes.
Glia
; 2024 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38794866
3.
The intellectual disability PAK3 R67C mutation impacts cognitive functions and adult hippocampal neurogenesis.
Hum Mol Genet
; 29(12): 1950-1968, 2020 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31943058
4.
Co-culture of exogenous oligodendrocytes with unmyelinated cerebella: Revisiting ex vivo models and new tools to study myelination.
Glia
; 69(8): 1916-1931, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33811384
5.
Dp71 contribution to the molecular scaffold anchoring aquaporine-4 channels in brain macroglial cells.
Glia
; 69(4): 954-970, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33247858
6.
PAK3 mutations responsible for severe intellectual disability and callosal agenesis inhibit cell migration.
Neurobiol Dis
; 136: 104709, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31843706
7.
The intellectual disability protein PAK3 regulates oligodendrocyte precursor cell differentiation.
Neurobiol Dis
; 98: 137-148, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27940202
8.
Expression of Dystrophin Dp71 Splice Variants Is Temporally Regulated During Rodent Brain Development.
Mol Neurobiol
; 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38802640
9.
Alteration of synaptic network dynamics by the intellectual disability protein PAK3.
J Neurosci
; 32(2): 519-27, 2012 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22238087
10.
The p21-activated kinase PAK3 forms heterodimers with PAK1 in brain implementing trans-regulation of PAK3 activity.
J Biol Chem
; 287(36): 30084-96, 2012 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22815483
11.
The molecular basis of p21-activated kinase-associated neurodevelopmental disorders: From genotype to phenotype.
Front Neurosci
; 17: 1123784, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36937657
12.
Pharmacological Inhibition of p-21 Activated Kinase (PAK) Restores Impaired Neurite Outgrowth and Remodeling in a Cellular Model of Down Syndrome.
Neurotox Res
; 41(3): 256-269, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36867391
13.
Challenges in glioblastoma research: focus on the tumor microenvironment.
Trends Cancer
; 9(1): 9-27, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36400694
14.
p21-Activated kinase 3 (PAK3) protein regulates synaptic transmission through its interaction with the Nck2/Grb4 protein adaptor.
J Biol Chem
; 286(46): 40044-59, 2011 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21949127
15.
PAK3 is a key signature gene of the glioma proneural subtype and affects its proliferation, differentiation and growth.
Cell Oncol (Dordr)
; 44(6): 1257-1271, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34550532
16.
The four mammalian splice variants encoded by the p21-activated kinase 3 gene have different biological properties.
J Neurochem
; 106(3): 1184-97, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18507705
17.
Challenges in glioblastoma research: focus on the tumor microenvironment: (Trends in Cancer, 9:1 p:9-27, 2023).
Trends Cancer
; 9(8): 692, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-36997420
18.
Regulation of the RAP1/RAF-1/extracellularly regulated kinase-1/2 cascade and prolactin release by the phosphoinositide 3-kinase/AKT pathway in pituitary cells.
Endocrinology
; 147(12): 6036-45, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16935846
19.
Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.
Front Cell Neurosci
; 10: 289, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28066185
20.
Overexpressed Down Syndrome Cell Adhesion Molecule (DSCAM) Deregulates P21-Activated Kinase (PAK) Activity in an In Vitro Neuronal Model of Down Syndrome: Consequences on Cell Process Formation and Extension.
Neurotox Res
; 30(1): 76-87, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26966010