Detalhe da pesquisa
1.
Next Generation of Fluorometric Protease Assays: 7-Nitrobenz-2-oxa-1,3-diazol-4-yl-amides (NBD-Amides) as Class-Spanning Protease Substrates.
Chemistry
; 29(50): e202301855, 2023 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37313627
2.
Hic Sunt Dracones: Molecular Docking in Uncharted Territories with Structures from AlphaFold2 and RoseTTAfold.
J Chem Inf Model
; 63(7): 2218-2225, 2023 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36884022
3.
SAR of novel benzothiazoles targeting an allosteric pocket of DENV and ZIKV NS2B/NS3 proteases.
Bioorg Med Chem
; 47: 116392, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34509861
4.
Naphthoquinones as Covalent Reversible Inhibitors of Cysteine Proteases-Studies on Inhibition Mechanism and Kinetics.
Molecules
; 25(9)2020 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32354191
5.
New Cysteine Protease Inhibitors: Electrophilic (Het)arenes and Unexpected Prodrug Identification for the Trypanosoma Protease Rhodesain.
Molecules
; 25(6)2020 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32210166
6.
Identification of sortase substrates by specificity profiling.
Bioorg Med Chem
; 25(18): 5002-5007, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28684010
7.
Non-covalent dyes in microscale thermophoresis for studying RNA ligand interactions and modifications.
Chem Sci
; 14(36): 9827-9837, 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37736627
8.
Impact of the Recognition Part of Dipeptidyl Nitroalkene Compounds on the Inhibition Mechanism of Cysteine Proteases Cruzain and Cathepsin L.
ACS Catal
; 13(9): 6289-6300, 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37180968
9.
Designing photoaffinity tool compounds for the investigation of the DENV NS2B-NS3 protease allosteric binding pocket.
RSC Med Chem
; 14(11): 2365-2379, 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37974966
10.
The effects of allosteric and competitive inhibitors on ZIKV protease conformational dynamics explored through smFRET, nanoDSF, DSF, and 19F NMR.
Eur J Med Chem
; 258: 115573, 2023 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37379675
11.
Impact of the Warhead of Dipeptidyl Keto Michael Acceptors on the Inhibition Mechanism of Cysteine Protease Cathepsin L.
ACS Catal
; 13(20): 13354-13368, 2023 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37881790
12.
A low-cost 3D-printable differential scanning fluorometer for protein and RNA melting experiments.
HardwareX
; 11: e00256, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35509940
13.
Identification of novel small-molecular inhibitors of Staphylococcus aureus sortase A using hybrid virtual screening.
J Antibiot (Tokyo)
; 75(6): 321-332, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35440771
14.
BANΔIT: B'-Factor Analysis for Drug Design and Structural Biology.
Mol Inform
; 40(1): e2000144, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32830452
15.
2-Sulfonylpyrimidines as Privileged Warheads for the Development of S. aureus Sortase A Inhibitors.
Front Mol Biosci
; 8: 804970, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35047562
16.
Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure-Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo Studies.
J Med Chem
; 64(16): 12322-12358, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34378914
17.
FINDUS: An Open-Source 3D Printable Liquid-Handling Workstation for Laboratory Automation in Life Sciences.
SLAS Technol
; 25(2): 190-199, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-31540570
18.
Modular Solid-Phase Synthesis of Antiprotozoal Barnesin Derivatives.
Org Lett
; 22(10): 3744-3748, 2020 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32212714
19.
Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase A.
ChemMedChem
; 15(10): 839-850, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32118357
20.
Proline-Based Allosteric Inhibitors of Zika and Dengue Virus NS2B/NS3 Proteases.
J Med Chem
; 62(24): 11359-11382, 2019 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31769670