Detalhe da pesquisa
1.
Novel multifunctional tacrine-donepezil hybrids against Alzheimer's disease: Design synthesis and bioactivity studies.
Arch Pharm (Weinheim)
; : e2300575, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593283
2.
Association between Albumin Alterations and Renal Function in Patients with Type 2 Diabetes Mellitus.
Int J Mol Sci
; 25(6)2024 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38542146
3.
Exopolysaccharides from vaginal lactobacilli modulate microbial biofilms.
Microb Cell Fact
; 22(1): 45, 2023 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36890519
4.
Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease.
Bioorg Med Chem
; 91: 117419, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37487339
5.
Determination of Effective Albumin in Patients With Decompensated Cirrhosis: Clinical and Prognostic Implications.
Hepatology
; 74(4): 2058-2073, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33710623
6.
Targeting neuronal calcium channels and GSK3ß for Alzheimer's disease with naturally-inspired Diels-Alder adducts.
Bioorg Chem
; 129: 106152, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36155094
7.
Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase.
Chembiochem
; 22(9): 1597-1608, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33400854
8.
Bio-Guided Fractionation of Stem Bark Extracts from Phyllanthus muellarianus: Identification of Phytocomponents with Anti-Cholinesterase Activity.
Molecules
; 26(14)2021 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34299650
9.
From Combinations to Single-Molecule Polypharmacology-Cromolyn-Ibuprofen Conjugates for Alzheimer's Disease.
Molecules
; 26(4)2021 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33669839
10.
New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators.
Molecules
; 26(11)2021 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34071439
11.
Solid Lipid Microparticles for Oral Delivery of Catalase: Focus on the Protein Structural Integrity and Gastric Protection.
Mol Pharm
; 17(9): 3609-3621, 2020 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32786955
12.
Unveiling the molecular mechanisms underpinning biorecognition of early-glycated human serum albumin and receptor for advanced glycation end products.
Anal Bioanal Chem
; 412(18): 4245-4259, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32367292
13.
N-1,2,3-triazole-isatin derivatives for cholinesterase and ß-amyloid aggregation inhibition: A comprehensive bioassay study.
Bioorg Chem
; 98: 103753, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32200328
14.
Unveiling the Biochemistry of the Epigenetic Regulator SMYD3.
Biochemistry
; 58(35): 3634-3645, 2019 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31389685
15.
Tacrines as Therapeutic Agents for Alzheimer's Disease. IV. The Tacripyrines and Related Annulated Tacrines.
Chem Rec
; 19(5): 927-937, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30489012
16.
QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer's Disease Therapy.
Molecules
; 24(8)2019 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30999586
17.
Exploiting the Chalcone Scaffold to Develop Multifunctional Agents for Alzheimer's Disease.
Molecules
; 23(8)2018 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061534
18.
Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis.
Molecules
; 23(3)2018 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29534488
19.
Imidazopyranotacrines as Non-Hepatotoxic, Selective Acetylcholinesterase Inhibitors, and Antioxidant Agents for Alzheimer's Disease Therapy.
Molecules
; 21(4): 400, 2016 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27023499
20.
From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold.
Bioorg Med Chem Lett
; 25(14): 2804-8, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26003339