Detalhe da pesquisa
1.
Development of a stereoselective and scalable process for the preparation of a methylcyclobutanol-pyridyl ether.
Bioorg Med Chem
; 26(4): 938-944, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28751197
2.
MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition.
J Pharmacol Exp Ther
; 355(3): 397-409, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26407721
3.
Pyrazoloquinolines as PDE10A inhibitors: discovery of a tool compound.
Bioorg Med Chem Lett
; 22(3): 1335-9, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22227212
4.
Evolution of the total synthesis of (-)-okilactomycin exploiting a tandem oxy-cope rearrangement/oxidation, a Petasis-Ferrier union/rearrangement, and ring-closing metathesis.
J Am Chem Soc
; 131(6): 2348-58, 2009 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19170499
5.
Total synthesis of (-)-okilactomycin.
J Am Chem Soc
; 129(48): 14872-4, 2007 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-17997560
6.
Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO Inhibitor.
J Med Chem
; 60(9): 3851-3865, 2017 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28322556
7.
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity.
J Med Chem
; 60(7): 2983-2992, 2017 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28245354
8.
Solution to the C3-Arylation of Indazoles: Development of a Scalable Method.
Org Lett
; 18(13): 3218-21, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27336404
9.
Relative rate profile for ring-closing metathesis of a series of 1-substituted 1,7-octadienes as promoted by a 4,5-dihydroimidazol-2-ylidene-coordinated ruthenium catalyst.
Org Lett
; 5(6): 789-92, 2003 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12633072
10.
Total syntheses of the assigned structures of lituarines B and C.
J Am Chem Soc
; 130(2): 422-3, 2008 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-18095694