Detalhe da pesquisa
1.
Automated Bioanalytical Workflow for Ligand Binding-Based Pharmacokinetic Assay Development.
Anal Chem
; 96(1): 488-495, 2024 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38156369
2.
Validation of a multiplexed and targeted lipidomics assay for accurate quantification of lipidomes.
J Lipid Res
; 63(6): 100218, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35489416
3.
Direct Analysis from Phase-Separated Liquid Samples using ADE-OPI-MS: Applicability to High-Throughput Screening for Inhibitors of Diacylglycerol Acyltransferase 2.
Anal Chem
; 93(15): 6071-6079, 2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33819010
4.
Spatial and temporal studies of metabolic activity: contrasting biochemical kinetics in tissues and pathways during fasted and fed states.
Am J Physiol Endocrinol Metab
; 316(6): E1105-E1117, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30912961
5.
High-Throughput Bioassays using "Dip-and-Go" Multiplexed Electrospray Mass Spectrometry.
Angew Chem Int Ed Engl
; 58(49): 17594-17598, 2019 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31589796
6.
Quantitation of a Therapeutic Antibody in Serum Using Intact Sequential Affinity Capture, Trypsin Digestion, and LC-MS/MS.
Anal Chem
; 90(1): 866-871, 2018 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29206445
7.
Generic automated method for liquid chromatography-multiple reaction monitoring mass spectrometry based monoclonal antibody quantitation for preclinical pharmacokinetic studies.
Anal Chem
; 86(17): 8776-84, 2014 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25010922
8.
Quantitative LC-MS/MS. 1. Impact of Points across a Peak on the Accuracy and Precision of Peak Area Measurements.
J Am Soc Mass Spectrom
; 34(6): 1136-1144, 2023 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37141514
9.
Ultrahigh-Throughput Intact Protein Analysis with Acoustic Ejection Mass Spectrometry.
J Am Soc Mass Spectrom
; 34(1): 4-9, 2023 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36468949
10.
Investigating Performance of the SLIM-Based High Resolution Ion Mobility Platform for Separation of Isomeric Phosphatidylcholine Species.
J Am Soc Mass Spectrom
; 34(10): 2176-2186, 2023 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37703523
11.
Intact Mass Quantitation of Therapeutic Antibodies for Pharmacokinetic Studies Using Immuno-Purification.
Methods Mol Biol
; 2313: 259-268, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34478143
12.
A Model-Based Approach to Bridging Plasma and Dried Blood Spot Concentration Data for Phase 3 Verubecestat Trials.
AAPS J
; 24(3): 53, 2022 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35384522
13.
An Investigation of Instability in Dried Blood Spot Samples for Pharmacokinetic Sampling in Phase 3 Trials of Verubecestat.
AAPS J
; 24(3): 52, 2022 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35384529
14.
Participant experiences using novel home-based blood collection device for viral load testing in HIV cure trials with analytical treatment interruptions
HIV Res Clin Pract
; 23(1): 76-90, 2022 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35968737
15.
Preliminary Acceptability of a Home-Based Peripheral Blood Collection Device for Viral Load Testing in the Context of Analytical Treatment Interruptions in HIV Cure Trials: Results from a Nationwide Survey in the United States.
J Pers Med
; 12(2)2022 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35207719
16.
"We are looking at the future right now": community acceptability of a home-based viral load test device in the context of HIV cure-related research with analytical treatment interruptions in the United States.
HIV Res Clin Pract
; 23(1): 120-135, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35348047
17.
Plasma-based approach to measure target engagement for liver-targeting stearoyl-CoA desaturase 1 inhibitors.
J Lipid Res
; 52(8): 1494-9, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21642745
18.
Novel cytochrome P450-mediated ring opening of the 1,3,4-oxadiazole in setileuton, a 5-lipoxygenase inhibitor.
Drug Metab Dispos
; 39(5): 763-70, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21325431
19.
Digitally Enabled, Patient-Centric Clinical Trials: Shifting the Drug Development Paradigm.
Clin Transl Sci
; 14(2): 445-459, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33048475
20.
Intact Protein Mass Spectrometry for Therapeutic Protein Quantitation, Pharmacokinetics, and Biotransformation in Preclinical and Clinical Studies: An Industry Perspective.
J Am Soc Mass Spectrom
; 32(8): 1886-1900, 2021 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32869982