Detalhe da pesquisa
1.
Total Chemical Synthesis of Aggregation-Prone Disulfide-Rich Starfish Peptides.
Chemistry
; 30(33): e202400933, 2024 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38609334
2.
Noncovalent Peptide Stapling Using Alpha-Methyl-l-Phenylalanine for α-Helical Peptidomimetics.
J Am Chem Soc
; 145(37): 20242-20247, 2023 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37439676
3.
Bi-allelic variants in INSL3 and RXFP2 cause bilateral cryptorchidism and male infertility.
Hum Reprod
; 38(7): 1412-1423, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37208861
4.
Molecular Profiling of VGluT1 AND VGluT2 Ventral Subiculum to Nucleus Accumbens Shell Projections.
Neurochem Res
; 48(8): 2490-2501, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37017888
5.
Further Developments towards a Minimal Potent Derivative of Human Relaxin-2.
Int J Mol Sci
; 24(16)2023 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37628851
6.
A Lipidated Single-B-Chain Derivative of Relaxin Exhibits Improved In Vitro Serum Stability without Altering Activity.
Int J Mol Sci
; 24(7)2023 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37047588
7.
A Real-Time, Plate-Based BRET Assay for Detection of cGMP in Primary Cells.
Int J Mol Sci
; 23(3)2022 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163827
8.
Probing the correlation between ligand efficacy and conformational diversity at the α1A-adrenoreceptor reveals allosteric coupling of its microswitches.
J Biol Chem
; 295(21): 7404-7417, 2020 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32303636
9.
The anti-fibrotic actions of relaxin are mediated through AT2 R-associated protein phosphatases via RXFP1-AT2 R functional crosstalk in human cardiac myofibroblasts.
FASEB J
; 34(6): 8217-8233, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32297670
10.
Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists.
Bioorg Chem
; 110: 104782, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33730669
11.
High-Throughput Screening Campaign Identified a Potential Small Molecule RXFP3/4 Agonist.
Molecules
; 26(24)2021 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34946593
12.
An apically located hybrid guanylate cyclase-ATPase is critical for the initiation of Ca2+ signaling and motility in Toxoplasma gondii.
J Biol Chem
; 294(22): 8959-8972, 2019 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30992368
13.
High-throughput screening campaign identifies a small molecule agonist of the relaxin family peptide receptor 4.
Acta Pharmacol Sin
; 41(10): 1328-1336, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32235863
14.
AT1R-AT2R-RXFP1 Functional Crosstalk in Myofibroblasts: Impact on the Therapeutic Targeting of Renal and Cardiac Fibrosis.
J Am Soc Nephrol
; 30(11): 2191-2207, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31511361
15.
Distinct but overlapping binding sites of agonist and antagonist at the relaxin family peptide 3 (RXFP3) receptor.
J Biol Chem
; 293(41): 15777-15789, 2018 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30131340
16.
Binding conformation and determinants of a single-chain peptide antagonist at the relaxin-3 receptor RXFP3.
J Biol Chem
; 293(41): 15765-15776, 2018 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30131342
17.
Chronic activation of the relaxin-3 receptor on GABA neurons in rat ventral hippocampus promotes anxiety and social avoidance.
Hippocampus
; 29(10): 905-920, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30891856
18.
Optimization and 13CH3 methionine labeling of a signaling competent neurotensin receptor 1 variant for NMR studies.
Biochim Biophys Acta Biomembr
; 1860(6): 1372-1383, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29596791
19.
Challenges in the design of insulin and relaxin/insulin-like peptide mimetics.
Bioorg Med Chem
; 26(10): 2827-2841, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28988628
20.
International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides.
Pharmacol Rev
; 67(2): 389-440, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25761609