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1.
Multimed Syst ; 28(1): 113-120, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-33976474

RESUMO

In this paper, linear regression (LR), multi-linear regression (MLR) and polynomial regression (PR) techniques are applied to propose a model Li-MuLi-Poly. The model predicts COVID-19 deaths happening in the United States of America. The experiment was carried out on machine learning model, minimum mean square error model, and maximum likelihood ratio model. The best-fitting model was selected according to the measures of mean square error, adjusted mean square error, mean square error, root mean square error (RMSE) and maximum likelihood ratio, and the statistical t-test was used to verify the results. Data sets are analyzed, cleaned up and debated before being applied to the proposed regression model. The correlation of the selected independent parameters was determined by the heat map and the Carl Pearson correlation matrix. It was found that the accuracy of the LR model best-fits the dataset when all the independent parameters are used in modeling, however, RMSE and mean absolute error (MAE) are high as compared to PR models. The PR models of a high degree are required to best-fit the dataset when not much independent parameter is considered in modeling. However, the PR models of low degree best-fits the dataset when independent parameters from all dimensions are considered in modeling.

2.
Sci Eng Ethics ; 21(1): 19-28, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24469471

RESUMO

This paper attempts to give an insight into emerging ethical issues due to the increased usage of the Internet in our lives. We discuss three main theoretical approaches relating to the ethics involved in the information technology (IT) era: first, the use of IT as a tool; second, the use of social constructivist methods; and third, the approach of phenomenologists. Certain aspects of ethics and IT have been discussed based on a phenomenological approach and moral development. Further, ethical issues related to social networking sites are discussed. A plausible way to make the virtual world ethically responsive is collective responsibility which proposes that society has the power to influence but not control behavior in the virtual world.


Assuntos
Ética , Internet/ética , Princípios Morais , Mídias Sociais/ética , Rede Social , Tecnologia/ética , Humanos , Desenvolvimento Moral , Controles Informais da Sociedade , Sociologia
3.
Complex Intell Systems ; 7(6): 3211-3224, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34777978

RESUMO

A massive amount of textual data now exists in digital repositories in the form of research articles, news articles, reviews, Wikipedia articles, and books, etc. Text clustering is a fundamental data mining technique to perform categorization, topic extraction, and information retrieval. Textual datasets, especially which contain a large number of documents are sparse and have high dimensionality. Hence, traditional clustering techniques such as K-means, Agglomerative clustering, and DBSCAN cannot perform well. In this paper, a clustering technique especially suitable to large text datasets is proposed that overcome these limitations. The proposed technique is based on word embeddings derived from a recent deep learning model named "Bidirectional Encoders Representations using Transformers". The proposed technique is named as WEClustering. The proposed technique deals with the problem of high dimensionality in an effective manner, hence, more accurate clusters are formed. The technique is validated on several datasets of varying sizes and its performance is compared with other widely used and state of the art clustering techniques. The experimental comparison shows that the proposed clustering technique gives a significant improvement over other techniques as measured by metrics such Purity and Adjusted Rand Index.

4.
IEEE/ACM Trans Comput Biol Bioinform ; 18(4): 1524-1534, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-31567100

RESUMO

Life threatening diseases like adult T-cell leukemia, neurodegenerative diseases, and demyelinating diseases such as HTLV-1 based myelopathy/tropical spastic paraparesis (HAM/TSP), hypocalcaemia, and bone lesions are caused by a group of human retrovirus known as Human T-cell Lymphotropic virus (HTLV). Out of the four different types of HTLVs, HTLV-1 is most prominent in scourging over 20 million people around the world and still not much effort has been made in understanding the epidemiology and controlling the prevalence of this virus. This condition further worsens when most of the infected cases remain asymptomatic throughout their lifetime due to the limited diagnostic methods; that are most of the times unavailable for timely detection of infected individuals. Moreover, at present, there is no licensed vaccination for HTLV-1 infection. Therefore, there is a need to develop the faster and efficient diagnostic method for the detection of HTLV-1. Influenced from the outcomes of the machine learning techniques in the field of bio-informatics, this is the first study in which 64 hybrid machine learning techniques have been proposed for the prediction of different type of HTLVs (HTLV-1, HTLV-2, and HTLV-3). The hybrid techniques are built by permutation and combination of four classification methods, four feature weighting, and four feature selection techniques. The proposed hybrid models when evaluated on the basis of various model evaluation parameters are found to be capable of efficiently predicting the type of HTLVs. The best hybrid model has been identified by having accuracy, an AUROC value, and F1 score of 99.85 percent, 0.99, and 0.99, respectively. This kind of the system can assist the current diagnostic system for the detection of HTLV-1 as after the molecular diagnostics of HTLV by various screening tests like enzyme-linked immunoassay or particle agglutination assays there is always a need of confirmatory tests like western blotting, immuno-fluorescence assay, or radio-immuno-precipitation assay for distinguishing HTLV-1 from HTLV-2. These confirmatory tests are indeed very complex analytical techniques involving various steps. The proposed hybrid techniques can be used to support and verify the results of confirmatory test from the protein mixture. Furthermore, better insights about the virus can be obtained by exploring the physicochemical properties of the protein sequences of HTLVs.


Assuntos
Biologia Computacional/métodos , Infecções por HTLV-I , Vírus Linfotrópico T Tipo 1 Humano , Aprendizado de Máquina , Algoritmos , Infecções por HTLV-I/epidemiologia , Infecções por HTLV-I/virologia , Humanos , Modelos Estatísticos , Proteínas Virais/química , Proteínas Virais/genética
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