Detalhe da pesquisa
1.
Species differences and human relevance of the toxicity of 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors and a new approach method in vitro for investigation.
Arch Toxicol
; 97(4): 991-999, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36800004
2.
Evaluation of human relevance of Nicofluprole-induced rat thyroid disruption.
Toxicol Appl Pharmacol
; 435: 115831, 2022 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34922950
3.
Primary Human Hepatocyte Spheroids as Tools to Study the Hepatotoxic Potential of Non-Pharmaceutical Chemicals.
Int J Mol Sci
; 22(20)2021 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34681664
4.
Comparison of in vitro thyroxine (T4) metabolism between Wistar rat and human hepatocyte cultures.
Toxicol In Vitro
; 96: 105763, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38142784
5.
Mapping Interindividual Variability of Toxicodynamics Using High-Throughput Transcriptomics and Primary Human Hepatocytes from Fifty Donors.
Environ Health Perspect
; 132(3): 37005, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38498338
6.
Plateable cryopreserved human hepatocytes for the assessment of cytochrome P450 inducibility: experimental condition-related variables affecting their response to inducers.
Xenobiotica
; 42(10): 968-79, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22515431
7.
Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes.
Toxicol In Vitro
; 73: 105107, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33545341
8.
Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis.
Cells
; 9(4)2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32295224
9.
Utility of Extrapolating Human S1500+ Genes to the Whole Transcriptome: Tunicamycin Case Study.
Bioinform Biol Insights
; 14: 1177932220952742, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33088175
10.
Three-Dimensional Spheroid Primary Human Hepatocytes in Monoculture and Coculture with Nonparenchymal Cells.
Tissue Eng Part C Methods
; 24(9): 534-545, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30101670
11.
Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study.
Toxicol Sci
; 162(2): 655-666, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29329425
12.
Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors.
Eur J Pharm Sci
; 109: 96-110, 2017 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28778465
13.
Drug-induced cholestasis risk assessment in sandwich-cultured human hepatocytes.
Toxicol In Vitro
; 34: 179-186, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27046439
14.
Cytotoxicity evaluation using cryopreserved primary human hepatocytes in various culture formats.
Toxicol Lett
; 258: 207-215, 2016 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27363785